Naringin–Chalcone Bioflavonoid-Protected Nanocolloids: Mode of Flavonoid Adsorption, a Determinant for Protein Extraction

Abstract

In order to highlight the applications of bioflavonoids in materials chemistry, naringin and its chalcone form were used in the nanomaterial synthesis to produce flavonoid-conjugated nanomaterials in aqueous phase. Chalcone form proved to be excellent reducing as well as stabilizing agent in the synthesis of monodisperse Au, Ag, and Pd nanoparticles (NPs) of ∼5–15 nm, following in situ reaction conditions where no external reducing or stabilizing agents were used. The mechanism of NP surface adsorption of flavonoid was determined with the help of dynamic light scattering and zeta potential measurements. Surface-adsorbed flavonoids also allowed NPs to easily transfer into the organic phase by using aqueous insoluble ionic liquid. Pd NPs attracted the excessive amount of surface adsorption of both naringin as well as its chalcone form that in turn drove Pd NPs in self-assembled state in comparison to Au or Ag NPs. An amount of surface-adsorbed flavonoids selectively determined the extraction of protein fractions from complex zein corn starch protein solution. Self-assembled Pd NPs with a large amount of surface-adsorbed naringin preferentially extracted zein fraction of higher molar mass, whereas Au and Ag NPs almost equally extracted the zein fractions of lower molar masses.

On the Use of Phenolic Compounds Present in Citrus Fruits and Grapes as Natural Antioxidants for Thermo-Compressed Bio-Based High-Density Polyethylene Films

“…For the UV–Vis spectra of the bio-HDPE films containing the natural antioxidants, major changes were observed in the band at approximately 205 nm, which can be related to the π → π* transitions within the aromatic ring of the phenolic molecules. For the NAR-containing bio-HDPE sample, the flavanone glycoside also showed the characteristic contributions for ring 1 and 2 structures, which were seen as low-intense and flat peaks at 284 and 324 nm, respectively [ 50 , 51 ]. In the spectrum of the bio-HDPE sample containing GA, in addition to the strong peak at 205 nm, showing oversaturation, a new peak appeared at 254 nm that is also due to the aromatic ring of the phenolic acid [ 52 ].…”

Nanotechnology Applications of Flavonoids for Viral Diseases

“…For encapsulation, metallic nanoparticles including superparamagnetic iron oxide nanoparticles (SPION) have been tried for quercetin, but this line of approach (SPION) despite its advantages (superparamagnetic nature, high ratio of spin polarization, and elevated conductivity) has also failed due to metallic toxicity [328]. An interesting application of the flavonoid naringin was to use it in the chalcone form, which was then surface-absorbed to gold, silver, or lead nanoparticles for the extraction of zein; however, the method is yet to yield antiviral uses [329].…”

Reactive Extraction of Betaine from Sugarbeet Processing Byproducts

“…The technique has been evaluated for the recovery of metals, lanthanides, alcohols, antibiotics, phenols, vitamins, amines, and carboxylic acids from synthetically prepared aqueous solutions or complex media. 29 − 36 The use of an extraction agent in the organic phase that can interact with the target product is the main difference between reactive extraction and its original technique. This couples the advantage of chemical extraction with physical extraction, resulting in higher recovery efficiencies.…”

“…Reactive extraction has been identified as a promising technique for the recovery of biochemicals from dilute aqueous media and is preferred over other separation techniques due to its high efficiency, selectivity, operational practicality, and low-cost and energy demand. , Moreover, in situ and continuous operational capability enable its use for commercial purposes. The technique has been evaluated for the recovery of metals, lanthanides, alcohols, antibiotics, phenols, vitamins, amines, and carboxylic acids from synthetically prepared aqueous solutions or complex media. − The use of an extraction agent in the organic phase that can interact with the target product is the main difference between reactive extraction and its original technique. This couples the advantage of chemical extraction with physical extraction, resulting in higher recovery efficiencies .…”