2024
DOI: 10.1002/tox.24378
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Naringin Induces ROS‐Stimulated G1 Cell‐Cycle Arrest and Apoptosis in Nasopharyngeal Carcinoma Cells

Chan‐Hung Chen,
Ni Tien,
Chun‐Hsu Yao
et al.

Abstract: Naringin, a bioflavonoid compound from grapefruit or citrus, exerts anticancer activities on cervical, thyroid, colon, brain, liver, lung, thyroid, and breast cancers. The present investigation addressed exploring the anticancer effects of naringin on nasopharyngeal carcinoma (NPC) cells. Naringin exhibits a cytotoxic effect on NPC‐TW 039 and NPC‐TW 076 cells with IC50 372/328 and 394/307 μM for 24 or 48 h, respectively, while causing little toxicity toward normal gingival epithelial (SG) cells (>500/500 μM… Show more

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