Naringin supplementation lowers plasma lipids and enhances erythrocyte antioxidant enzyme activities in hypercholesterolemic subjects

Jung, Un Ju; Kim, H J; Lee, J S; Lee, M K; Kim, H O; Park, E J; Kim, H K; Jeong, Tae Sook; Choi, Myung‐Sook

doi:10.1016/s0261-5614(03)00059-1

Cited by 225 publications

(147 citation statements)

References 54 publications

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“…Clinical trials have linked increasing intake of flavonoids with a reduced occurrence of breast cancer in humans (Bosetti et al, 2005). Flavonoids also reduce several risk factors for cardiovascular diseases in human (Arai et al, 2000), lowers total and low density lipoproteins (LDL) cholesterol in plasma and liver (Jung et al, 2003). They improve vasodilation and vaso-relaxation preventing the formation of potentially damaging clots and subsequent stroke.…”

Section: Volume 40mentioning

confidence: 99%

Utilization Potentials of Moringa oleifera in Nigeria: A Preliminary Assessment

Stevens

Ugese²,

Baiyeri

2015

ILNS

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A survey on the utilization potentials of Moringa oleifera in Nigeria was conducted in 2011. The survey involved 14 states (including the Federal Capital Territory) across the five agroecological zones. The 14 States were Borno, Kano, Adamawa, Kebbi, Kaduna, Niger, Nassarawa, Abuja (F.C.T), Kogi, Benue, Kwara, Oyo, Enugu and Anambra. A semi-structured questionnaire and field visits were adopted in this study while a multistage random sampling technique was used in selecting the respondents. The survey found more than 25 local names of Moringa oleifera in Nigeria. Widespread utilization of Moringa as food was observed with its use as vegetable in soup, as salad or herbal tea having particularly high scores. There was low awareness of Moringa oleifera as a domestic cleansing agent although about 30% of respondents used it in domestic water clarification. The species has high ethno-medicinal value, addressing close to 20 conditions including typhoid and malaria fever (78.7%), ear infection (71.8%), eye infection (66.9%), lowering of blood sugar (diabetes mellitus) (65.2%) and blood pressure (64.7%). It is evident that this important species is still underutilized in Nigeria and more efforts are required for a fuller exploitation of its rich potentials.

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Section: Volume 40mentioning

confidence: 99%

Utilization Potentials of Moringa oleifera in Nigeria: A Preliminary Assessment

Stevens

Ugese²,

Baiyeri

2015

ILNS

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“…La actividad de la catalasa en eritrocitos ha sido empleada como uno de los indicadores del status oxidativo en seres humanos. Fueron encontradas alteraciones en su actividad en función de la dieta y del ejercicio [26][27][28][29] . La dieta puede interferir en el estatus oxidativo.…”

Section: Influencia De La Dab Sobre La Actividad De Las Enzimas Antiounclassified

“…Una dieta puede llevar a una disminución de la actividad de la catalasa si ella proveer al organismo moléculas antioxidantes capaces de eliminar radicales superóxido y peróxido de hidrógeno. Al mismo tiempo, algunos suplementos alimentares, como la naringina, flavonóide reductor de los niveles de lipídios plasmáticos, y la vitamina C, pueden llevar a una protección antioxidante por un mecanismo opuesto, elevando la actividad catalásica 27,28 . Los resultados presentados en este trabajo demuestran que la dieta afro-bahiana por si sola, no interfiere en la actividad basal de la catalasa, cuando comparada a los controles.…”

Section: Influencia De La Dab Sobre La Actividad De Las Enzimas Antiounclassified

Dieta afro-bahiana, estrés oxidativo y ejercício físico

et al. 2006

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El objetivo de este trabajo fue estudiar el efecto de la dieta afro-bahiana sobre el estrés oxidativo inducido por el ejercicio físico extenuante en 17 individuos jóvenes y saludables. MétodosLa dieta afro-bahiana se compone principalmente de carne roja, aceite de palma, zumo de frutas, raíces, harina de mandioca y cereales. El control alimenticio se extendió por 4 meses. Antes del control alimenticio, se retiraron muestras de sangre en estado basal y cinco minutos después de un ejercicio físico extenuante en tapiz rodante. El mismo procedimiento fue seguido después del control alimenticio. Para analizar el efecto de la dieta y del ejercicio físico extenuante se compararon los indicadores antioxidantes, catalasa y superóxido dismutasa y el estrés oxidativo por la peroxidación lipídica, determinada por el análisis del malonaldeído en eritrocitos. ResultadosLos resultados muestran que la dieta, en condición de reposo, no influenció significativamente el estatus antioxidante de las enzimas catalasa y superóxido dismutasa ni la concentración de análisis del malonaldeído. Se observa, no obstante, que después de un ejercicio físico extenuante, la actividad de la catalasa, tanto con dieta libre como después de la dieta afro-bahiana, aumentó de forma significativa (p<0,05) en 19,49 y 11,74%, respectivamente. La actividad del superóxido dismutasa y concentración de análisis del malonaldeído no se alteraron. La actividad de la catalasa después del ejercicio físico extenuante fue significativamente menor (p<0,05) después de la dieta afro-baiana (26,11%).

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“…Compared to other flavonoids, rutin is considered as a nontoxic and nonoxidizable molecule [38]. Both naringin and naringenin are strong antioxidants [39,40]. However, the former is less potent compared with the latter because the sugar moiety in naringin causes steric hindrance of the scavenging group.…”

Section: Quantification and Biological Importancementioning

confidence: 99%

LC-MS Analysis of Phenolic Acids, Flavonoids and Betanin from Spineless Opuntia ficus-indica Fruits

Slimen¹,

Mabrouk²,

Chaâbane³

et al. 2017

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Abstract:Opuntia ficus-indica belongs to the Cactaceae family and is widespread in semi-arid and arid regions. Cactus pears are known for their health promoting properties which are due to a variety of bioactive molecules. This study aims to identify and quantify phenolic acids, flavonoids and betanin from spineless Opuntia ficus-indica fruits. Fresh mature samples were crushed, and extracted with 50% aqueous ethanol. The identification process was carried out using a Shimadzu high performance liquid chromagraph equipped with a quadrupole mass spectrum. Quantification was made using calibration curves of analytical standards. 9 phenolic acids, 1 flavan-3-ol, 2 flavanones, 3 flavonols, 6 flavones and 2 betacyanins were identified. Important levels of betanin, quinic acid, cirsiliol, acacetin, transcinnamic acid, rutin and naringin were calculated. Our results indicated that Opuntia ficus-indica fruits are an important dietary source of phenolic compounds and betalains with high antioxidant capacity.

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Naringin supplementation lowers plasma lipids and enhances erythrocyte antioxidant enzyme activities in hypercholesterolemic subjects

Cited by 225 publications

References 54 publications

Utilization Potentials of <i>Moringa oleifera</i> in Nigeria: A Preliminary Assessment

Utilization Potentials of <i>Moringa oleifera</i> in Nigeria: A Preliminary Assessment

Dieta afro-bahiana, estrés oxidativo y ejercício físico

LC-MS Analysis of Phenolic Acids, Flavonoids and Betanin from Spineless <i>Opuntia ficus-indica</i> Fruits

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Naringin supplementation lowers plasma lipids and enhances erythrocyte antioxidant enzyme activities in hypercholesterolemic subjects

Cited by 225 publications

References 54 publications

Utilization Potentials of <i>Moringa oleifera</i> in Nigeria: A Preliminary Assessment

Utilization Potentials of <i>Moringa oleifera</i> in Nigeria: A Preliminary Assessment

Dieta afro-bahiana, estrés oxidativo y ejercício físico

LC-MS Analysis of Phenolic Acids, Flavonoids and Betanin from Spineless &lt;i&gt;Opuntia ficus-indica&lt;/i&gt; Fruits

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Product

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LC-MS Analysis of Phenolic Acids, Flavonoids and Betanin from Spineless <i>Opuntia ficus-indica</i> Fruits