Nasal Carriage of Staphylococcus Aureus among Apparently Healthy School Children in Owerri Metropolis, Nigeria

Prevalence and Antibiotic Susceptibility Pattern of Staphylococcus Aureus Isolated from Various Clinical Specimens in South East Nigeria

“…The organisms exhibit remarkable versatility in their behavior towards antibiotics, with some strains having become resistant to most commonly used antibiotics. 34 In our results, we observed high level of resistance of S. aureus strain to penicillin G (81.7%), ampicillin (76.9%), Nalidixic acid (72.1%), and chloramphenicol (70.1%), which is in accordance with our previous study in Owerri 35 and the reports of Tiwari et al 36 The high frequency of resistance observed in these antibiotics could be attributed to their use in treatment of diseases in animals and humans. This implies that these antibiotics are no longer be effectively used as empirical therapy for S. aureus infections particularly in the study area.…”

“…The resistance of S. aureus isolates to commonly used antibiotics in Nigeria and other different parts of the world has been widely reported. [10][11][12][13][14][15][16] This increased emergence of resistant strains has being attributed to the indiscriminate use of antibiotics in both human and veterinary medicine especially in the developing countries. Since the emergence of S. aureus strains with resistance to methicillin shortly after its introduction into clinical medicine, 17 it has established itself as a leading agent for a wide range of infections.…”

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“…The prevalence of S. aureus nasal carriage rate of 56.3% observed in this study is similar to previous findings by Chigu and Ezeronye [26] who reported 50% nasal colonization in both hospital and non-hospital subjects in Aba, Abia State Nigeria and Nsofor et al [13] which reported 62.9% carriage in school children in Elele, Rivers State Nigeria. In contrary, Onanuga and Temedie [12] reported a lower S. aureus nasal colonization rate (33.3%) in healthy inhabitants of Amassoma in Niger delta region of Nigeria and Adesida et al [27] reported a much lower (14.0%) nasal colonization in medical students in Lagos, Nigeria.…”

“…Nasal carriage of S. aureus has been reported across various settings in Nigeria [8][9][10][11][12][13], and infections associated with S. aureus has also been reported in various parts of the country [14][15][16][17][18]. To the best of our knowledge, no population-based prevalence study has been carried out to determine Nasal carriage of S. aureus amongst school children in Owerri metropolis, Southeast Nigeria.…”

Nasal Carriage and Methicillin Resistance of Staphylococcus Aureus Among Schoolchildren in Sana’a City, Yemen

“…Our nding was also similar to those reported from other countries [18][19][20] . However, the nasal carriage rate of S. aureus in this study tends to be lower than that reported in Nigeria (56.3%), India (46.67%), United State of America (39.6%; age group 1-19 years old), Netherland (36%; age group 1-19 years, and Nepal (31%; age group less than 15 years old) [21][22][23][24][25] . On the other hand, the prevalence of S. aureus among school children in our study was higher than that reported in China (5.1%), Serbia (2.59%), and Iraq (17.75%) [26][27][28] .…”