Nasal Carriage of Staphylococcus Aureus in a Population of Healthy Nigerian Students

Abstract

SUMMARY. The nasal carrier-rate of Staphylococcus aureus in 548 Nigerians aged 9-32 years and attending various educational establishments was 56.4%. This rate decreased with increasing age. A significantly greater proportion of females (65.0%) than males (46.5%) were carriers, but the excess in females was apparent only in subjects aged >20 years. Mucoid strains of S . aureus, which gave a negative slide-coagulase reaction, were found in 21.5% of carriers aged 10-15 years, but were absent from members of other age-groups. A considerable proportion of all the strains tested were resistant to commonly used antibiotics.

Associated risk factors and pulsed field gel electrophoresis of nasal isolates of Staphylococcus aureus from medical students in a tertiary hospital in Lagos, Nigeria

“…The nasal carrier rate of S.aureus in this present study was 14%. This carriage rate correlates well with the results of Chigbu and Ezeronye [12] and the ranges described by Riewerts et al [19] but lower than the figures obtained in another Nigerian study [6]. This variation may be attributed to the population studied, the sampling and culture techniques.…”

“…This variation may be attributed to the population studied, the sampling and culture techniques. Lamikanra et al [6] observed that carriage rate of individuals from 9-32 years decrease progressively as the age increases. The present investigation has mean age of 24.…”

“…They observed that S. aureus increased in the nose of a group of Malays and Indian footballers during aerobic training probably due to high oxygen demand. Nasal carriage also varies among different ethnic and age groups [6,7]. There are considerable proofs that in healthcare settings, in-patients and hospital personnel are the main potential reservoirs of S.aureus.…”

Flora bacteriana nasal: estudo entre médicos residentes dos Hospitais Universitários de Londrina – Paraná

“…O número de Staphylococcus aureus resistente a 3 ou mais antibióticos foi de 9% em A, 0% em B e 55% em C. Com o Staphylococcus coagulase negativo obtiveram-se os seguintes resultados: no Grupo A 79% , 97% de B e 94% de C. Portanto, não se verificaram diferenças significativas entre as cepas resistentes de coagulase negativa entre os 3 grupos. Os autores obtiveram também 10% das cepas de coagulase negativa resistente a três (3) ou mais antibióticos do grupo A, 16% de B e 15% de C. Lamikanra et al(1985), ao estudarem a flora nasal de 548 estudantes nigerianos, identificaram 56,4% …”

Beta-lactamase Induction in Nosocomial Staphylococcus aureus Strains Cultured from the Nasal Cavity and Wound of Patients

“…aureus colonises the nasal mucosa of approximately 25-30% of apparently healthy population (Lamikanra, Paul, Akinwole, Paul, 1985;Yamamoto et al, 2010). This provides a reservoir from which it can be introduced when host defenses are breached, and has been reported to increase the risk for subsequent infections (Mahdi et al, 2000;Wertheim et al, 2005).…”