Nasal Cavity Schwannoma—A Case Report and Review of the Literature

Liao, Jyun-Yi; Lee, Herng‐Sheng; Kang, Bor‐Hwang

doi:10.1177/01455613211034598

Cited by 10 publications

(13 citation statements)

References 56 publications

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“…Schwannoma, benign encapsulated nerve sheath neoplasm, originates from the neuroectodermal schwann cells of sheaths of the cranial, peripheral, and autonomic nerve. [ 1 ] In 1935, the term neurilemmoma was given by Stout believing that tumor arose from cells of sheath of Schwann. [ 2 , 3 ] The first case of nasal septum schwannoma was described by Bogdasarian and Stout in 1943.…”

Section: Discussionmentioning

confidence: 99%

“…Sinonasal schwannomas are rare and account only about 4% of all head and neck schwannomas. [ 1 ] In sinonasal tract, the most common site involved is the ethmoid sinus followed by maxillary sinus, nasal cavity and sphenoid sinus. In nasal cavity, the nasal septum is rarer site.…”

Section: Discussionmentioning

confidence: 99%

“…Schwannoma, a rare slow-growing benign tumors, arise from Schwann cells of myelin sheath of peripheral nerve, autonomic nerves, and/or cranial nerves. [ 1 , 2 ] Mostly, they occur in middle-aged adults, without gender and race predilection. Schwannoma may occur anywhere in the body commonly occurring on flexor aspect of extremities, posterior spinal nerve roots, mediastinum, retroperitoneum, cerebellopontine angle, and head and neck region.…”

Section: Introductionmentioning

confidence: 99%

“…Schwannoma may occur anywhere in the body commonly occurring on flexor aspect of extremities, posterior spinal nerve roots, mediastinum, retroperitoneum, cerebellopontine angle, and head and neck region. [ 1 , 2 ] Of all the schwannoma, 25 to 45% are confined to the head and neck region, in which nasal cavity and paranasal sinuses contribute about 4% and nasal septum the rarest site. [ 1 , 2 ]…”

Section: Introductionmentioning

confidence: 99%

“…[ 1 , 2 ] Of all the schwannoma, 25 to 45% are confined to the head and neck region, in which nasal cavity and paranasal sinuses contribute about 4% and nasal septum the rarest site. [ 1 , 2 ]…”

Section: Introductionmentioning

confidence: 99%

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Schwannoma of the Nasal Septum: A Rare Clinicopathological Case Report in an 18-Year-Old Female

Kaushik

Rani

Kumar

et al. 2022

International Journal of Applied &Amp; Basic Medical Research

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Schwannoma, a benign tumor, arise from schwann cells of myelin sheath; occur anywhere in the body but commonly occur on flexor aspect of extremities. Nasal septum being the rarer site. We report a case of nasal septum schwannoma in an 18-year-old female presented with intermittent epistaxis and progressively increasing nasal obstruction for 2-year duration. The differential diagnosis of juvenile angiofibroma, pyogenic granuloma, and pleomorphic adenoma was made and complete surgical excision was done. Histopathological examination revealed ciliated stratified columnar epithelium, underlying tumor area with two distinct patterns, mainly hypercellular and few hypocellular areas. The cells have spindle shaped pointed basophilic nuclei with abundant eosinophilic cytoplasm. Overall feature was suggestive of nasal septum schwannoma. For confirmation, immunohistochemical staining with S-100 was done and tumor was found positive. Herein, we report the clinicopathological features of nasal septum schwannoma in an 18-year-old female.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Schwannoma of the Nasal Septum: A Rare Clinicopathological Case Report in an 18-Year-Old Female

Kaushik

Rani

Kumar

et al. 2022

International Journal of Applied &Amp; Basic Medical Research

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Paranasal Schwannomas: A Comprehensive Study of 2 Cases

Saito,

Tsuda,

Takeda

et al. 2023

Ear Nose Throat J

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Paranasal sinus tumors are a heterogeneous group of neoplasms (with paranasal schwannomas being a rare subtype) that are often present with non-specific symptoms, such as nasal obstruction and epistaxis. Thus, early diagnosis is crucial for optimal management. This study presents 2 cases of paranasal schwannomas, detailing their clinical presentation, diagnostic methods, and treatment approaches. Both patients underwent endoscopic sinus surgery with successful tumor excision and had no significant complications or recurrences during follow-up. Diagnosis was based on a combination of clinical examination, radiological imaging (computed tomography and magnetic resonance imaging), and histopathological confirmation with immunohistochemical staining. Treatment consisted primarily of endonasal resection, with consideration of frontal craniotomy if necessary. This study aims to contribute to the understanding of paranasal schwannomas and emphasizes the importance of early detection and treatment to improve patient outcomes.

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Intracapsular Enucleation of Brachial Plexus Schwannoma With Intraoperative Neuromonitoring: A Case Series Study and a Review of Literature

Shi,

He,

Dong

et al. 2023

Ear Nose Throat J

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Objective: Brachial plexus schwannoma (BPS) is a rare clinical entity that poses a significant challenge for head and neck surgeons due to its neuroanatomical complexity and potential severe complications, such as major motor or sensory neurological deficits or pain of the corresponding upper extremity. This article summarizes our experience in its diagnosis and intracapsular enucleation with intraoperative neuromonitoring (INM). Methods: A retrospective review of BPS cases treated at our tertiary medical institution was conducted between April 2020 and May 2023. The clinical and demographic data were retrieved from case notes. Results: Totally, 3 cases were included. All 3 patients were male, aged 43 to 54 years (median age = 52). The presenting symptom was a palpable supraclavicular mass in all these cases (2 on the left side and 1 on the right side). Neuromonitoring was performed with a 4-channel nerve integrity monitor, with the electrodes placed in the upper arm and forearm muscles, as demonstrated in the literature. After exposing the mass and identifying its origin from the brachial plexus, a unipolar stimulating probe was used to stimulate the tumor surface or the nerves with a 1.0-mA current, and a longitudinal incision into the tumor capsule was made along a carefully mapped line with no INM response. Then the mass was carefully exposed and meticulously dissected from its capsule to achieve an intact enucleation. Immediate postoperative neurological deficit was documented in Case 1 as a mild grasping weakness. The recovery of the other 2 patients was uneventful. The follow-up duration was 7 to 38 months (median = 8 months). The minor motor deficit of Case 1 recovered completely 1 month after surgery. No recurrence of BPS was observed. Conclusions: Intracapsular enucleation with INM could result in complete removal of BPS and minimal postoperative neurological deficit, whose recovery was quick and satisfactory.

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Nasal Cavity Schwannoma—A Case Report and Review of the Literature

Cited by 10 publications

References 56 publications

Schwannoma of the Nasal Septum: A Rare Clinicopathological Case Report in an 18-Year-Old Female

Schwannoma of the Nasal Septum: A Rare Clinicopathological Case Report in an 18-Year-Old Female

Paranasal Schwannomas: A Comprehensive Study of 2 Cases

Intracapsular Enucleation of Brachial Plexus Schwannoma With Intraoperative Neuromonitoring: A Case Series Study and a Review of Literature

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