Nasal Clearance in Monozygotic Twins^1–3

The Nose after Laryngectomy

“…The time elapsing before a sweet taste is detected reflects nasal mucociliary transport, which is directed posteriorly from anterior nares to nasopharynx. The technique, described by Andersen et al (1974), gives reliable and reproducible results when it is carried out under conditions of identical particle placement, temperature and humidity.…”

Human response to controlled levels of toluene in six-hour exposures.

“…In table 4 the arithmetic means and the standard errors of the means after 5 h of exposure to clean air are given for the different parameters measured in the fivechoice test, and the results of an analysis of variance are given in table 5. From this table it can be seen that no effects of the toluene exposures were found for any of the five-choice test parameters.…”

“…Forced expiratory vital capacity (FVC), forced expiratory volume in the first seeond after maximal inspiration (FEVl.o), and forced expiratory flow during exhalation of the middle part of FVC (FEF,,-,,) were measured with a single breath instrument (Vitalographa, Buckingham, United Kingdom). These techniques have been described in detail earlier (5,6,7). Functional residual capacity and airway resistance were measured in a whole-body plethysmograph (Mercury) (13,14).…”

Mucociliary Clearance in Bronchiectasis

“…[11][12][13][14] Thus, the impaired mucociliary clearance can be explained on the basis of altered rheologic properties of secretions and defective cilia in patients with bronchiectasis. Methods to evaluate the nasal mucociliary clearance include direct observation of dyes or particles deposited on nasal mucosa, 15 use of radioactive microdroplets, 16 single radioactively tagged resin particles, 17 and radiopaque Teflon discs monitored by external device. 11 Andersen et al described a very simple method consisting of depositing a particle of saccharine on the nasal mucosa and observing the time when the subjects reported the first taste of sweetness.…”