Nasal high flow therapy introduction lowers reintubation risk in a Peruvian paediatric intensive care unit

Abstract

Despite improvements in global child mortality, more than 650 000 children under five die of lower respiratory infections every year. 1 The vast majority of these deaths occur in low-and middle-income countries, due to more restricted access to basic interventions like immunisations, antibiotics and supplemental oxygen. 2-4 Middle-income countries have a high burden of paediatric respiratory disease. They are also in a unique position to reduce respiratory-related mortality, by improving access to advanced respiratory support, such as mechanical ventilation and non-invasive respiratory support. Using mechanical ventilation leads to complications like ventilator-associated pneumonia, ventilator-induced lung injuries, laryngeal trauma and the prolonged use of sedative medications. Given these complications, many

Comparison of high flow oxygen therapy versus noninvasive mechanical ventilation for successful weaning from invasive ventilation in children: An observational study

“…[38] The PICU LOS and mortality rates were reported mostly similar between extubation to HFNC and NIMV, some reports stated shorter PICU LOS with HFNC compared to CPAP. [39] We found similar PICU LOS and mortality rates between the 2 groups. All these data suggest that HFNC and NIMV may provide comparable support for PERF in pediatric patients.…”