Nasal Malignancy Masquerading as Polyposis: Importance of Biopsy in Powered Endoscopic Sinus Surgery

Clinical value of office‐based endoscopic incisional biopsy in diagnosis of nasal cavity masses

“…The authors insist that all nasal polyps need histological examination. There are other reports in which the clinical impression with history, physical examination, and imaging was nasal polyp, but the pathology result was tumor 11–14. When patients had unilateral sinonasal lesions without bone destruction, neither CT nor MRI was useful in diagnosis of neoplasms except angiofibromas 15.…”

“…There are other reports in which the clinical impression with history, physical examination, and imaging was nasal polyp, but the pathology result was tumor. [11][12][13][14] When patients had unilateral sinonasal lesions without bone destruction, neither CT nor MRI was useful in diagnosis of neoplasms except angiofibromas. 15 The authors concluded that endonasal endoscopic biopsy is a qualitative diagnostic tool in the diagnosis of sinonasal neoplasm.…”

Intestinal‐type ethmoid adenocarcinoma in sinonasal polyposis

“…They are silent clinically for long periods and are discovered when their size reaches the middle meatus 2. Signs that suggest malignancy, such as unilateral nasal obstruction, bleeding, rhinorrhea, epistaxis, and unilateral neurologic alterations or recurrent facial pain, often are initially absent 4. None of these manifestations was present in our case.…”

“…This case illustrates the necessity of analyzing all of the tissue samples obtained from polypectomies, even in bilateral polypectomies 3. Although the incidence of malignancy in bilateral NP is rare, all polypoid masses in the nasal cavity or sinuses cannot be presumed to be benign 4…”

“…3 Although the incidence of malignancy in bilateral NP is rare, all polypoid masses in the nasal cavity or sinuses cannot be presumed to be benign. 4 Intestinal-type adenocarcinomas of the nose and sinuses are rare, accounting for less than 4% of all sinonasal cancers. They share histopathologic features with gastroenterologic adenocarcinomas and may appear sporadically or as metastases from glandular tumors.…”