Nasal pain disrupting sleep as a presenting symptom of extraesophageal acid reflux in children

Extraesophageal reflux in children

“…Symptoms identified during an otolaryngological assessment can be disparate (see Table 1 [ [16][17][18][19]). …”

Monitoring of gastric acid suppression in patients with extraesophageal reflux disease

“…Otolaryngologic manifestations of EERD in infants and children encompass cough [1], laryngitis [2], recurrent croup [3,4], laryngomalacia [5,6], apparent life threatening event [7], apnea [8], asthma [9], subglottic stenosis [10,11], chronic aspiration, sleep disorders [12], nasal pain [13], difficult to control laryngeal papilloma [30], chronic suppurative otitis media, otalgia, and rhinosinusitis [14,15,31]. The present study also included children with various manifestations of EERD.…”

“…Infants and children with extraesophageal reflux disease (EERD) may present with a wide variety of otolaryngologic signs and symptoms [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15]. The diagnosis of EERD may become challenging due to insufficient clinical history and varying sensitivity and specificity of available diagnostic tests [12].…”

Laryngopharyngeal reflux and chronic sinusitis

“…In children, cyclic vomiting has been associated with chronic sinusitis and GERD [ 6 ], although with subsequent therapy, these conditions were felt to be associated with, but not causing, the vomiting [ 7 ]. Nasal pain has also been described in a child with LPR that resolved after acid suppression [ 8 ]. However, despite the likelihood that LPR could contaminate the nose and sinuses, and thus predispose the patient to recurrent and chronic sinus disease, the evidence in published studies has received only a "C" rating (case series or extrapolations from cohort or case-control studies) [ 9 ].…”