Nasal Polyposis and Its Association with Cardiac Functions

Dhiman, Sapna; Dhiman, Abhishek; Azad, Ramesh K.; Negi, Prakash Chand; Lal, Bhushan; Thakur, Jagdeep S

doi:10.1159/000517976

Med Princ Pract

2021

DOI: 10.1159/000517976

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Nasal Polyposis and Its Association with Cardiac Functions

Sapna Dhiman

Abhishek Dhiman

Ramesh K. Azad

et al.

Abstract: Highlights of the Study• Upper respiratory airway obstruction is found to be associated with snoring and hypoxia, causing cardiac dysfunctions. • We evaluated the effect of nasal polyps and of their treatment on cardiac functions. • Significant improvement was observed in cardiac functions of subjects treated by sinus surgery.

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Cited by 2 publications

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Is endoscopic sinus surgery sufficient to modify the evolution of adult AERD? Aspirin desensitization as a maintenance factor: systematic review

Conti,

Correa,

Scadding

2023

Front. Allergy

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IntroductionAspirin desensitization (AD) and aspirin therapy after desensitization (ATAD) are therapeutic interventions for patients with aspirin-exacerbated respiratory disease (AERD). Our aim is to investigate whether its addition to endoscopic sinus surgery (ESS) improves the overall prognosis of the disease.MethodsA systematic review of the current literature including adult patients with a positive diagnosis of AERD undergoing endoscopic sinus surgery (ESS) in the context or in absence of upper airway comorbidity, prior to AD + ATAD.ConclusionThis review concludes that the surgical approach is beneficial in AERD, but its effects are short—lived. Surgery should be considered initially with subsequent AD + ATAD in AERD patients, due to the sustained improvement achieved compared to those receiving ESS alone.

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Is endoscopic sinus surgery sufficient to modify the evolution of adult AERD? Aspirin desensitization as a maintenance factor: systematic review

Conti,

Correa,

Scadding

2023

Front. Allergy

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Observation of the protagonist effect of body fluid load in the pathogenesis of sinonasal polyposis

Abhinandan,

Shekhar,

Krishna

et al. 2024

Journal of Indira Gandhi Institute of Medical Sciences

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Background: The objective is to assess the association of body fluid load in the pathogenesis of sinonasal polyposis. Subjects and Methods: The targeted cases with chronic rhinosinusitis (CRS) with nasal polyposis and control of CRS without polyposis were randomly taken from the admitted patients. Two groups of 30 people each were taken. Demographic details such as name, age, and gender were noted. Excess body water was then calculated by subtracting the perfect body water from the total body water (TBW). Results: Of 30 cases and 30 controls aged 18–60, the median was 30.5, and the mean was 34 ± 12.8 years. The gender of the case was 18 males and 12 females, while in control, the males and females were of equal number. The mean TBW was 34.4 ± 5.27 L in cases and 32.4 ± 5.87 L in controls. Total body weight was found to be higher in cases than in controls but not found to be statistically significant (P = 0.160). Excess body water was found in 60% of nasal polyps cases and 46.7% of controls, which was statistically insignificant (P = 0.301). Conclusion: There is a complex interplay between our body fluid dynamics and nasal polyp pathogenesis in CRS with polyposis. While our findings suggest potential trends with small sample sizes, further research with more extensive and diverse populations is needed to authenticate and expand on these observations.

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Nasal Polyposis and Its Association with Cardiac Functions

Cited by 2 publications

References 13 publications

Is endoscopic sinus surgery sufficient to modify the evolution of adult AERD? Aspirin desensitization as a maintenance factor: systematic review

Is endoscopic sinus surgery sufficient to modify the evolution of adult AERD? Aspirin desensitization as a maintenance factor: systematic review

Observation of the protagonist effect of body fluid load in the pathogenesis of sinonasal polyposis

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