Nasal retainers have been utilized to maintain the position of the nose after primary rhinoplasty in cleft lip patients. However, commercial nasal retainers made from silicone are quite expensive. To address this issue, the authors designed an alternative nasal retainer that is affordable, safe, and has similar biomechanical and biocompatibility properties to other commercial nasal retainers. Three types of nasal retainers were tested: our own (Nostriloo), a commercial nasal retainer from Turkey, and another one from Taiwan. There were 3 samples on each group, with a total sample of 9 retainers. Each sample was tested for biomechanical property and biocompatibility. Elasticity modulus, tensile strength, and direct and indirect toxicity were analyzed. Nostriloo had the least durable tensile strength but showed similar elastic modulus (2.76 ± 0.41 MPa) compared with human lower lateral cartilage (2.09 ± 0.81 MPa). On the basis of direct and indirect toxicity tests, Nostriloo is considered nontoxic. Nostriloo can be utilized for small-scale production and use. Further experiment is needed to produce higher-quality nasal retainers.