2017
DOI: 10.18875/2375-7043.4.302
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Nasal Septum Perforation due to Cocaïne Abuse

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“…Cocaine produces vasoconstriction and may cause necrosis in the nasal mucosae, cartilage and also damaging the osseous portion of the nasal septum. Impurities found in cocaine (mannitol, amphetamines, talcum powder) may cause an inflammatory local reaction which leads to granulation tissue, deterioration of the ciliary function and mucosal erosion, contributing to the perforation pathogenesis 8,9 .…”
Section: Traumamentioning
confidence: 99%
“…Cocaine produces vasoconstriction and may cause necrosis in the nasal mucosae, cartilage and also damaging the osseous portion of the nasal septum. Impurities found in cocaine (mannitol, amphetamines, talcum powder) may cause an inflammatory local reaction which leads to granulation tissue, deterioration of the ciliary function and mucosal erosion, contributing to the perforation pathogenesis 8,9 .…”
Section: Traumamentioning
confidence: 99%