Nasopharyngeal carcinoma with orbital invasion

Hsu, Wen-Ming; Wang, A. G.

doi:10.1038/sj.eye.6701358

Cited by 41 publications

(29 citation statements)

References 8 publications

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“…11,12 NPC with orbital invasion, however, is rarely reported in the literature. NPC is a highly infiltrative tumor and can invade the orbit via several routes.…”

Section: Discussionmentioning

confidence: 99%

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Nasopharyngeal carcinoma presenting as proptosis in a child: a diagnostic dilemma

Sharma

Ahluwalia

Singhal

et al. 2015

Int J Otorhinolaryngol Head Neck Surg

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<p class="abstract">Nasopharyngeal carcinoma (NPC), although rare but does occur in pediatric age group and can present with variable non-specific signs and symptoms. The objective of this report is to emphasize that, because of its rarity, it is not clinically suspected and kept in differential diagnosis of nasopharyngeal mass in children, leading to delayed diagnosis and significant therapeutic implications. We hereby, describe a case of 10 year old boy who presented with bilateral cervical lymphadenopathy and simultaneously developing proptosis of the left eye, which is one of the important rare manifestation of NPC, that creates a diagnostic challenge.</p>

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“…11,12 NPC with orbital invasion, however, is rarely reported in the literature. NPC is a highly infiltrative tumor and can invade the orbit via several routes.…”

Section: Discussionmentioning

confidence: 99%

“…Orbital involvement from NPC is seen in 3.2% of cases. 12 Diagnostic evaluation of NPC is done by multidisciplinary team approach which is done by various methods which not only determine the extent of primary tumor but also the presence of metastasis. The most important is the clinical evaluation of the size and location of cervical lymph nodes.…”

mentioning

confidence: 99%

Nasopharyngeal carcinoma presenting as proptosis in a child: a diagnostic dilemma

Sharma

Ahluwalia

Singhal

et al. 2015

Int J Otorhinolaryngol Head Neck Surg

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“…Ophthalmic presentation as the initial presenting feature of nasopharyngeal carcinoma is uncommon. Patients may present with proptosis, diplopia, optic neuritis 19 . Orbital involvement from NPC is seen in 3.2% of cases 19 .Our case is free from orbital involvement.…”

Section: Discussionmentioning

confidence: 99%

“…Patients may present with proptosis, diplopia, optic neuritis 19 . Orbital involvement from NPC is seen in 3.2% of cases 19 .Our case is free from orbital involvement. Lateral and posterior extension of the primary growth itself may involve the lower cranial nerves exiting from jugular and hypoglossal foramina.…”

Section: Discussionmentioning

confidence: 99%

A Case Report of Nasopharngeal Carcinoma in Children presented with rt. Neck Mass

Morshed

Islam

Rahman

et al. 2015

J. paediatr. surg. Bangladesh

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Nasopharyngeal carcinoma is a rare disease in children. It present with mass in the nasopharynx or neck swelling. Recently a six year old boy was diagnosed as a case of NPC and treated with standard chemotherapy. The boy was presented with neck swelling, palatal palsy and ear discharge. The patient was diagnosed by lymph node biopsy and immunohistochemistry. The diagnosis was delayed for 4 months which usually occur in our country. He was diagnosed by lymph node biopsy and immunohistochemistry. He was treated with standard protocol based chemotherapy.

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“…Since the nasopharynx is relatively a clinically silent region; therefore, the first presentation may be with cervical nodal or distant metastasis. [2][3][4][5]7 Orbital involvement is seen in 3.2% of cases 8,9 and bilateral orbital invasion occurs in 0.7% of patients with nasopharyngeal carcinoma. 10 We report a case of aggressive nasopharyngeal carcinoma in a patient who presented with rapidly progressive diminution of vision.…”

Section: "Extensivementioning

confidence: 99%

Aggressive nasopharyngeal carcinoma presenting as diminution of vision: a case report

et al. 2013

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Nasopharyngeal carcinoma is a malignant disease and is more common in males than in females with M:F ratio of 3:1. It has a bimodal peak at 16-20 and 46-50 years of age. Orbital involvement is seen in 3.2% and bilateral orbital invasion occurs in 0.7% of patients with nasopharyngeal carcinoma. Imaging has significant role in detecting the early nasopharyngeal carcinoma, tumor staging, involvement of lymph node, monitoring the patients after the therapy, to detect recurrence and radiation associated changes in the soft tissue and bone. We report a case of aggressive nasopharyngeal carcinoma in 22 years old male who presented with rapidly progressive diminution of vision.

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Nasopharyngeal carcinoma with orbital invasion

Cited by 41 publications

References 8 publications

Nasopharyngeal carcinoma presenting as proptosis in a child: a diagnostic dilemma

Nasopharyngeal carcinoma presenting as proptosis in a child: a diagnostic dilemma

A Case Report of Nasopharngeal Carcinoma in Children presented with rt. Neck Mass

Aggressive nasopharyngeal carcinoma presenting as diminution of vision: a case report

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