Nasopharyngeal Symptoms in Patients with Obstructive Sleep Apnea Syndrome

Brander, Pirkko; Soirinsuo, M.; Lohela, P.

doi:10.1159/000029354

Cited by 76 publications

(62 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…4,5 Nevertheless, these adverse effects can cause patients discomfort and even lead to treatment cessation. 6,7 Previously, upper-airway complaints, especially rhinorrhea and sneezing, were assumed to increase during CPAP treatment. 6 Recently, however, we evaluated the nasal symptoms of 385 subjects before CPAP initiation and 2 months after and found that upperairway symptoms related to dry mucosa seemed to decrease during CPAP treatment.…”

Section: Introductionmentioning

confidence: 99%

“…6,7 Previously, upper-airway complaints, especially rhinorrhea and sneezing, were assumed to increase during CPAP treatment. 6 Recently, however, we evaluated the nasal symptoms of 385 subjects before CPAP initiation and 2 months after and found that upperairway symptoms related to dry mucosa seemed to decrease during CPAP treatment. 8 In that previous study, subjects received no humidification devices, whereas symptomatic subjects received topical medication (steroids and saline).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Persistence of Upper-Airway Symptoms During CPAP Compromises Adherence at 1 Year

2016

View full text Add to dashboard Cite

BACKGROUND:The most common adverse effects of CPAP are related to the upper airways. We evaluated upper-airway symptoms before and after a CPAP trial as well as their effect on CPAP adherence. We also evaluated the effect of humidification added to CPAP therapy on upper-airway symptoms. METHODS: We followed for 1 y 536 subjects with obstructive sleep apnea scheduled consecutively for CPAP initiation. Subjects completed visual analog questionnaires on nasal stuffiness, rhinorrhea, and mouth dryness (0 ‫؍‬ no symptoms, 100 ‫؍‬ severe symptoms). RESULTS: Before CPAP initiation, mean nasal stuffiness score was 29.6 ؎ 24.9, rhinorrhea score was 16.0 ؎ 21.7, and mouth dryness score was 43.8 ؎ 33.1. In subjects who quit CPAP treatment before the 1-y follow-up, the increase in rhinorrhea score during CPAP initiation was significant, 5.3 (95% CI 0.5-9.5, P ‫؍‬ .02), and in those using CPAP at 1 y, nasal stuffiness score and mouth dryness score decreased significantly during initiation, ؊5.1 (95% CI ؊7.9 to ؊2.4, P < .001) and ؊21.2 (؊25.5 to ؊17.4, P < .001). Mouth dryness score decreased significantly with CPAP regardless of humidification: change with humidification, ؊18.1 (95% CI ؊22.1 to ؊14.3), P < .001; change without, ؊10.5 (95% CI ؊16.9 to ؊4.1), P ‫؍‬ .002. Humidification also prevented the aggravation of rhinorrhea (change, ؊0.4 [95% CI ؊2.6 to 1.9], P ‫؍‬ .75) and alleviated nasal stuffiness (change ؊5.3 [95% CI ؊7.8 to ؊2.6], P < .001) with CPAP, whereas its absence induced a significant rise in symptom scores: change in rhinorrhea, 11.5 (95% CI 7.1-16.7), P < .001; change in nasal stuffiness, 8.5 (95% CI 3.9 -13.5, P < .001). CONCLUSIONS: The severity of upper-airway symptoms before CPAP does not predict CPAP use at 1 y, whereas CPAP non-users at 1 y had smaller or no alleviation in symptom scores during initiation compared with those who continued CPAP treatment.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Persistence of Upper-Airway Symptoms During CPAP Compromises Adherence at 1 Year

2016

View full text Add to dashboard Cite

show abstract

“…As complicações mais graves decorrentes do uso de CPAP são previsíveis e raras. As complicações mais descritas na literatura compreendem: desconforto torácico; piora da congestão nasal e rinorréia, em pacientes com rinite alérgi-ca; pneumotórax; pneumoencéfalo; algia em seios da face; sinusopatia; ressecamento nasal; enfisema subcutâneo de pálpebras inferiores; aerofagia e epistaxe 18,19 . Para alguns autores alguns sintomas nasofaríngeos apresentados durante o tratamento são preocupantes e podem levar a falta de adesão a terapia 20,21 .…”

Section: Discussionunclassified

“…O uso contínuo do CPAP nasal nos pacientes com SAOS e asma grave (possíveis respiradores orais), faz com que estes passem a respirar pelo nariz durante o sono, restituindo a fisiologia normal das VAS, contribuindo assim para redução da intensidade de sintomas nasofaríngeos 19 .…”

Section: Discussionunclassified

Eventos adversos nasofaríngeos da pressão positiva contínua em vias aéreas em pacientes com asma grave e apneia obstrutiva do sono

Landeiro¹,

Salles²,

Amaral³

et al. 2015

cmbio

View full text Add to dashboard Cite

Introdução: Pacientes com asma grave e síndrome da apneia obstrutiva do sono (SAOS) apresentam frequência elevada de sintomas sugestivos de rinite, tais como ressecamento nasal e de faringe, rinorréia e espirros que podem ser agravados com o tratamento com pressão positiva contínua nas vias aéreas (CPAP). O CPAP constitui-se em uma das opções terapêuticas para indivíduos com SAOS moderada e grave. Apesar de efetivo, a adesão ao CPAP nasal (nCPAP) é variável, sendo a intolerância à máscara e a presença de sintomas nasofaríngeos problemas clínicos observados. Objetivo: descrever os efeitos adversos nasofaríngeos da nCPAP durante a titulação em pacientes com asma grave e SAOS. Metodologia: Foram avaliados 21 indivíduos asmáticos adultos de ambos os sexos, admitidos no Programa de Controle da Asma na Bahia. Todos realizaram polissonografia basal e com titulação de CPAP; receberam orientação sobre o tratamento e foram submetidos a um criterioso ajuste da máscara. Resultado: Entre os pacientes estudados, 20 (95,2%) apresentaram sintomas nasofaríngeos durante a titulação de CPAP. Ressecamento de faringe e oral foram os sintomas mais frequentes, pois estiveram presentes em 12 (57,0%) e 8 (38,1%) dos pacientes. Outros sintomas relatados foram: 7 (33,4%) cefaleia, 6 (28,5%) obstrução nasal, 6 (28,5%) prurido nasal, 4 (19,1%) ressecamento nasal, 4 (19,1%) dor compressiva, 3 (14,2%) rinorréia, 3 (14,2%) lesão na pele, 2 (9,6%) ressecamento ocular e 1 (4,8%) espirros. Conclusão: Pacientes asmáticos submetidos à terapia com nCPAP apresentaram<span style="background-image: initial; background-attachment: initial; background-size: initial; background-origin: initial; background-clip: initial; background-position: initial; background-repeat: initial;"> elevada frequência de ressecamento oral e de faringe.

show abstract

“…17,18 Çeşitli çalışmalarda hava yolunun kuruluğu en sık karşı-laşılan yakınmalardan biri olarak bildirilmiştir. 19,20 Eğer hastada nazal konjesyon, kuruluk, epistaksis veya rinit varsa ısı-nemlendirme ünitesi ekleme, nazal tuzlu-su lavajı, antihistaminik, nazal steroid veya oronazal maske kullanı-mı yararlı olabilir. Bu çalışmada PAP kullanmamanın en nadir nedenleri olarak burun tıkanıklığı (%9,7) ve burun akıntısı (%2,4) bildirilmiştir.…”

unclassified

Factors Effecting the Compliance of Positive Airway Pressure Therapy in Patients with Sleep Related Breathing Disorders

Uçar¹,

Olcay²,

Demir³

et al. 2011

Solunum

View full text Add to dashboard Cite

ÖZETAmaç: Pozitif hava yolu basıncı (PAP) tedavisi, düzenli kullanılma koşuluyla uyku ile ilişkili solunum bozukluğunun (USB) en etkili tedavi yöntemidir. PAP tedavisine uyum, USB bulunan hastaların etkin tedavisi ve tedavi izlemi için önemlidir. Bu çalışmada PAP tedavisine uyumu iyi olmayan USB olan hastalarda uyumu bozan etkenleri araştırmayı amaçladık. O sırada PAP tedavisi kullanımı ortalama 10,2 ay takip sonrası; 85 (%67,4) hastada ortalama haftada 6,8 gün ve gecede 6,5 saat olarak saptandı. PAP tedavisi kullanmadığını bildiren 41 hastada tedavi kullanım süresi ortancası iki ay olarak bulundu. PAP kullanmamanın ana nedenleri sıklık sırasıyla maske sorunu 9 (%21,9), basıncı tolere edememe 8 (%19,5), boğulma hissi 7 (%17,0) ve maske ile uyumakta güçlük 5 (%12,1) olarak bildirildi. Uyumun kötü olması, uyumu iyi olan hastalara gore, uyku latansının uzun (>30 dakika: %24,6 ve %10,3), uyku bölünmesi-nin sık (%49,1 ve %29,4) ve dinlendirici olmayan uykunun az sık-lıkta olması (%63,2 ve %92,6) ile ilişkiliydi. Gereç ve ABSTRACTAim: Positive airway pressure (PAP) treatment is the most efficient treatment of sleep related breathing disorders (SRBD) when used regularly. Data on the compliance of PAP therapy is important in the management and follow-up of patients with sleep SRBD. The purpose of this study was to investigate the reasons of noncompliance for PAP therapy in patients with SRBD. Material and Methods:The study enrolled 125 patients, who received diagnosis of SRBD in polysomnography between 2006 and 2007 in the sleep disorders clinic. Patients were contacted about 12 months later and answered a telephone administered questionnaire, with information on characteristics of sleep.

show abstract

Nasopharyngeal Symptoms in Patients with Obstructive Sleep Apnea Syndrome

Cited by 76 publications

References 19 publications

Persistence of Upper-Airway Symptoms During CPAP Compromises Adherence at 1 Year

Persistence of Upper-Airway Symptoms During CPAP Compromises Adherence at 1 Year

Eventos adversos nasofaríngeos da pressão positiva contínua em vias aéreas em pacientes com asma grave e apneia obstrutiva do sono

Factors Effecting the Compliance of Positive Airway Pressure Therapy in Patients with Sleep Related Breathing Disorders

Contact Info

Product

Resources

About