Nasopharyngeal Tuberculosis: Manifestations between 1991 and 2000

Abstract

Nasopharyngeal tuberculosis commonly presents with cervical lymphadenopathy. The differential diagnosis of tuberculosis from nasopharyngeal carcinoma is difficult. In the patients who have cervical lymphadenopathy and no other identified causes, biopsy of nasopharynx would give an additive information for diagnosis.

Primary tuberculosis of the eustachian tube causing otitis media with effusion

“…In this case, the center of lesion was within ET boundary and the patient's chief complaints were mainly otologic symptoms such as aural fullness and hearing disturbance [4,5]. Although the most common presenting symptoms of nasopharyngeal tuberculosis is cervical lymphadenopathy (91.3%) [3], no significant cervical lymphadenopathy was observed in this case. From these findings, we concluded this case as primary tuberculosis arising in the ET, not the nasopharynx.…”

“…It may be ambiguous to differentiate between nasopharyngeal tuberculosis and ET tuberculosis definitely. Nasopharyngeal tuberculosis can infiltrate ET lumen secondarily, and this is often reported [3]. However, primary ET tuberculosis means primary tumors arising from ET, which is a very rare clinical entity.…”

Nasopharyngeal tuberculosis

“…8 The minimum period of instituting the treatment in this extra-pulmonary tuberculosis is 6 months. 9 Six month regimen consisting of Isoniazid, Rifampicin, Pyrazinamide and Ethambutol for two months on the initial phase followed by Isoniazid and Rifampicin for 4 months as the continuation phase has been advocated. 10 While the six-month treatment may be sufficient for many patients, each patient has to be individually assessed and, where relevant, treatment duration may have to be extended for a given patient.…”

Primary nasopharyngeal tuberculosis mimicking exacerbation of chronic rhinosinusitis

“…1,6 The most common clinical presentation of nasopharyngeal tuberculosis is cervical lymphadenopathy. 2,3 The upper cervical lymph nodes are predominantly affected, making the clinical picture almost indistinguishable from that of nasopharyngeal carcinoma. Otological symptoms (e.g.…”

“…[1][2][3] Primary nasopharyngeal tuberculosis is described as isolated infection of the nasopharynx in the absence of pulmonary or systemic disease. It is an even more unusual condition, with just a few case reports in the English language literature.…”