Nasopharynx and Oropharynx

Abstract

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Epipharyngeal Abrasive Therapy (EAT) Reduces the mRNA Expression of Major Proinflammatory Cytokine IL-6 in Chronic Epipharyngitis

“…The epipharynx, which has well-developed submucosal lymphoid tissue, is responsible for host defense mucosal immunity, but it is also susceptible to local inflammation due to upper respiratory tract infection (URTI), air pollution, and pollen [ 1 , 2 ]. The ciliated structure of the epipharyngeal mucosa highly expresses various virus entry factors, suggesting the importance of the epipharynx in URTI [ 3 , 4 ]. Epipharyngitis is involved not only in otolaryngological disorders, but also in the development of systemic diseases such as IgA nephropathy, palmoplantar pustulosis, rheumatic arthritis, psoriasis, myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), and Long COVID [ 1 , 5 , 6 , 7 , 8 , 9 ].…”