National Cancer Mortality-to-Incidence Ratio (MIR) in Iran (2005 - 2014)

Abstract

Background: Cancer is the first cause of death followed by ischemic heart disease (IHD) and stroke, worldwide, with increasing 19.5% years of life lost (YLL) due to cancer from 2007 to 2017. The cancer burden is steadily increased with decreasing 4.4% death rate from 2007-2017. The incidence rate of cancer is twice to 3 times higher in developed countries with low mortality due to care regarding developing countries. Objectives: Here, we report the 10 years' incidence and mortality of malignancies in Iran with different patterns compared to the other parts of the world. Methods: Data of national cancer registry system from 2005 to 2014 were analyzed in order to find out the trend of age standardized incidence rate (ASIR)/age standardized mortality rate (ASMR)/ mortality to incidence ratio (MIR) in both sexes in Iranian population. Results: Growing trend in ASIR for both sexes in all of the cancers were seen. ASMR decreased from 2005 to 2014 in both sexes with higher rate in males. MIR decreased by half in 2014 compared to 2005 regarding the increase of cancer in Iran. Conclusions: In Iran, the incidence of cancer is increasing due to aging people and death is decreasing due to the good care of patient. So, it is a good sample of developing country, which is comparable with the developed ones.

A rare FANCA gene variation as a breast cancer susceptibility allele in an Iranian population

“…In addition, breast cancer is an important public health issue; with ~8,000 women being diagnosed annually in Iran, of which 97.2% are women. However, due to the relatively early diagnosis, it is the fifth most common cause of cancer death in Iran ( 3 ). The two major susceptibility genes, BRCA1 and BRCA2 , account for a maximum of 20% of familial breast cancer cases worldwide.…”

Joint disease mapping of breast, uterine, and ovarian cancers in cities of Isfahan Province from 2005 to 2010 using spatial shared component model

“…In addition, breast cancer is known as the second cause of female death. [ 1 2 3 ] The incidence rate of this cancer is estimated 38 one per 100,000 ones as the commonest cause of female death between 45 and 55 year old ages. The standardized incidences of the mentioned cancer were reported 86.4, and 27.3% in developing countries and developed countries, respectively.…”

“…The standardized incidences of the mentioned cancer were reported 86.4, and 27.3% in developing countries and developed countries, respectively. [ 1 ] Uterine cancer is the third prevalent cancer and one death causes among female around the world. The lead of disease is seen in most countries, so that 86% of reported cases in developing countries.…”

“…However, it has increased in recent years in a way that breast cancer is known as the most prevalent malignancy among Iranian females. [ 1 ] Uterine cancer was known as the 10 th prevalent cancer (2.8%) among Iranian females in 2010. Ovarian cancer is the eight prevalent cancers and the 12 th cause of death in Iran.…”

Saving the Breast Saves the Lives of Breast Cancer Patients

“…In 2018, 18.1 million new cases were diagnosed with breast cancer, and 9.6 million deaths occurred due to cancer. Also, the 5-year prevalence was estimated to be 43.8 million in the world [1]. Nowadays, management of breast cancer is largely dependent on surgery, radiation, and systemic therapy.…”