National Heart Failure Registry, India: Design and methods

Abstract

Objective Heart failure (HF) has emerged as a global public health problem that affects both low and high-income countries. The high HF burden and the need for resource-intensive treatments often lead to health system crisis in resource-poor settings. Data on prevailing practice patterns and long-term clinical outcomes of HF are scarce from the low and middle-income countries. Nationally representative HF data from India are not available. Methods The National Heart Failure Registry (NHFR) is a multicentric, hospital-based registry of HF patients from 53 centers across India. Consecutive patients admitted with the diagnosis of acute decompensated HF satisfying the European Society of Cardiology (ESC) 2016 criteria will be enrolled into the registry from January 2019 to December 2019. Each participating center is expected to contribute 200 patients into the registry (i.e., more than 10,000 HF patients from India). We are collecting demographics, clinical, laboratory, imaging, and other diagnostic data at baseline from all registered patients in the registry by using a structured document. Additionally, we are collecting the details of treatment practices and the usage of guideline-directed therapy from all participants. We intend to obtain the in-hospital, 3-months, 6-months and one-year outcome data on mortality, cause of death, and repeated hospitalization events. Conclusions In summary, NFHR will be the first nationally representative HF registry aimed at providing crucial information on prevailing etiology, distribution and current practices in the management of HF.

Clinical profile and 90 day outcomes of 10 851 heart failure patients across India: National Heart Failure Registry

“…The design and detailed methods of the NHFR have been published earlier. 12 In brief, the NHFR is a facility-based registry of ADHF patients admitted to 53 hospitals in 21 states and four union territories in India. The overall recruitment period was from January 2019 to July 2020.…”

Toward a Universal Definition of Etiologies in Heart Failure: Categorizing Causes and Advancing Registry Science

“…To better understand the current state of HF surveillance, we asked participating registry leaders to provide current demographic data of enrolled participants and case report form details. 5,8–29 The Figure shows an overview of selected registries, led by investigators participating in this viewpoint, which were largely region-specific (eg, Asian Sudden Cardiac Death in Heart Failure, The European Society of Cardiology Heart Failure Long-Term Registry, the Sub-Saharan Africa Survey of Heart Failure, Gulf CARE), country-specific (eg, Get With The Guidelines-Heart Failure, Change the Management of Patients With Heart Failure registry, National Cardiovascular Data Registry Practice Innovation and Clinical Excellence, Indian National HF Registry) or state/city-specific (eg, Kerala HF Registry, Trivandrum HF Registry) and include participants from each World Health Organization region. We acknowledge that this is not a comprehensive listing of all available registries, but a selected group.…”

Assessment of the impact of heart failure on household economic well-being: a protocol

“…The study will be developed under the platform of the National Heart Failure Registry (NHFR). The details of NHFR are published elsewhere 10 . Briefly, 54 hospitals from different states of India are participating and recruiting patients in the NHFR.…”

“…The ETL is divided into 4 categories; the states with ratios of 0•56-0•75 (low ETLs), 0•41-0•55 (lower-middle ETLs), 0•31-0•40 (highermiddle ETLs), and less than 0•31 (high ETLs). For our study, we will group the low and lower-middle ETL (0•41-0•75) into one group, and retained the higher-middle ETL (0•31-0•40) and high ETL (<0•31) categories 3,10 . From each of the three selected regions based on the ETL classification, 6-8 hospitals will be identified.…”