AIM:To evaluate the frequency of Helicobacter pylori (H. pylori ) reinfection in peptic ulcer patients during 9 years after H. pylori eradication.
METHODS:We invited 117 peptic ulcer patients in whom eradication of H. pylori was confirmed 1 year after eradication treatment both by histology and by rapid urease test. In total, 57 patients were available for the study procedures: 34 (59.6%) male, 23 (40.4%) female; mean age 52.3 ± 13.0 years. There were 45 (78.9%) patients with duodenal ulcer and 12 (21.1%) with gastric ulcer. H. pylori was diagnosed by a rapid urease test and histology if endoscopy was performed.If endoscopy was refused, H. pylori was diagnosed by the C14-urea breath test and serology. H. pylori was established if at least one of the tests was positive.
RESULTS:The mean follow-up was 8.9 ± 1.0 years (range, 6-12