National trend survey of hospitalized patients with febrile seizure in the United States

Abstract

Several studies have reported the prevalence and incidence of febrile seizure (FS) among children in the USA and other countries. However, recent trends in FS among hospitalized children, hospital course, and risk factors for its severity remain unknown at a national level in the USA. Method: Hospital discharge records of patients with FS aged <6 years were obtained for the years 2003, 2006, 2009, and 2012 from the Kid's Inpatient Database. Data were weighted to estimate the annual hospitalization rates with respect to gender and race/ethnicity in the United States. Multivariable logistic regression was conducted to ascertain factors associated with FS severity. Results: A decreasing trend in total annual hospitalization rates due to FS was observed, ranging from 59.0 per 100,000 children in 2003 to 40.8 per 100,000 children in 2012 (p < 0.001). Winter predominance of hospitalizations was observed (p = 0.001). Hispanic children and children admitted to hospitals in northeast region were less likely to be severely affected. Age, gender, health insurance status, and household income level were not associated with FS severity. Conclusions: Total hospitalization rates due FS is decreasing, and race/ethnicity and geographic locations of the patients were associated with FS severity.

An observational epidemiological study of febrile convulsion due to urinary tract infection

“…They also reported a cumulative incidence rate of 4.1% for FC which is approximately similar to our results. However our study confirms higher prevalence rate of FC among boys population, gender distribution has not been supported by literature review (20).…”

Recent practice patterns in diagnostic procedures anticonvulsants, and antibiotics for children hospitalized with febrile seizure

“…Febrile seizure (FS) is the most common type of seizure observed in children. FS is characterized by episodes of convulsions that occur in association with fever in children aged between 3 months and 6 years without a central nervous system infections or electrolyte imbalance [1][2][3][4][5]. FS is believed to be a benign seizure syndrome, and is distinct from other neurologic disorders.…”

Trends of neuraminidase inhibitors use in children with influenza related respiratory infections

“…This illness holds significance for public health because it occurs in outbreaks worldwide every year, especially during fall and winter seasons . The vast majority of patients with influenza experience mild illness, but influenza may develop complications, such as lower respiratory infections, febrile seizure, and encephalopathy, which can result in hospitalizations . Neuraminidase inhibitors are recommended for children hospitalized with influenza, and the rationale of its use is to shorten durations of symptoms, and prevent potential complications such as comorbid otitis media …”

“…seizure, and encephalopathy, which can result in hospitalizations. [3][4][5] Neuraminidase inhibitors are recommended for children hospitalized with influenza, and the rationale of its use is to shorten durations of symptoms, and prevent potential complications such as comorbid otitis media. 3,6 Four types of neuraminidase inhibitors are currently available for children with influenza in Japan; oseltamivir, zanamivir, laninamivir, and peramivir.…”