National Trends in Allergic Rhinitis and Chronic Rhinosinusitis and COVID-19 Pandemic-Related Factors in South Korea, from 1998 to 2021

Lee, Hojae; Park, Jaeyu; Lee, Myeongcheol; Kim, Hyeon Jin; Kim, Minji; Kwon, Rosie; Lee, Seung Won; Koyanagi, Ai; Smith, Lee; Kim, Min Seo; Rhee, Sang Youl; Cho, Joong Ki; Kim, Sunyoung; Rahmati, Masoud; Yon, Dong Keon

doi:10.1159/000535648

Cited by 7 publications

(2 citation statements)

References 10 publications

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“…Additionally, the objective of our study was to investigate the risk factors associated with atopic dermatitis. Patients with AD were defined by positive responses to two questions: “Have you ever been diagnosed AD by a doctor within the past 12 months?” and “Have you ever been diagnosed AD by a doctor throughout life?” In addition, the questions were used the same during the study 11 , 19 , 20 .…”

Section: Methodsmentioning

confidence: 99%

National prevalence of atopic dermatitis in Korean adolescents from 2009 to 2022

Kattih,

Lee,

et al. 2024

Sci Rep

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Previous studies have examined the prevalence of allergic diseases in adolescents 1–2 years after the emergence of the COVID-19 pandemic. However, more data is needed to understand the long-term impact of COVID-19 on allergic diseases. Thus, we aimed to examine the trend of the atopic dermatitis prevalence in Korean adolescents before and during the COVID-19 pandemic across 14 years. Additionally, we analyze the risk factors of atopic dermatitis (AD) based on the results. The Korean Disease Control and Prevention Agency conducted the Korea Youth Risk Behavior Web-based Survey from 2009 to 2022, from which the data for this study were obtained. Prevalence trends were compared across subgroups, and the β difference (βdiff) was calculated. We computed odds ratios to examine changes in the disease prevalence before and during the pandemic. This study included a total of 917,461 participants from 2009 to 2022. The prevalence of atopic dermatitis increased from 6.79% (95% CI 6.66–6.91) in 2009–2011 to 6.89% (95% CI 6.72–7.05) in 2018–2019, then decreased slightly to 5.82% (95% CI 5.60–6.04) in 2022. Across the 14 years, middle school student status, low parent’s highest education level, low household income, non-alcohol consumption, non-smoker smoking status, no suicidal thoughts, and no suicide attempts were associated with increased risk of atopic dermatitis, while female sex, rural residence, high BMI, low school performance, low household income, and no feelings of sadness and despair was associated with a small increase. This study examined the prevalence of atopic dermatitis across an 18-year, and found that the prevalence increased in the pre-pandemic then decreased during the start of the pandemic and remained constant throughout the pandemic. This trend could be explained mainly by the large scale social and political changes that occurred during the COVID-19 pandemic.

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Section: Methodsmentioning

confidence: 99%

National prevalence of atopic dermatitis in Korean adolescents from 2009 to 2022

Kattih,

Lee,

et al. 2024

Sci Rep

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“…This is because the KNHANES data set targets all ages, and not just adolescents; hence, it lacks the specificity for adolescents compared with the KYRBS data set. However, this data set represents South Korea and is used in studies as an external validation for the KYRBS data set [39][40][41]. In addition, the risk calculator that we produced was purely created for academic purposes, and its application should be limited to that scope.…”

Section: Strengths and Limitationsmentioning

confidence: 99%

Machine Learning–Based Prediction of Suicidality in Adolescents With Allergic Rhinitis: Derivation and Validation in 2 Independent Nationwide Cohorts

Lee,

Cho,

Park

et al. 2024

J Med Internet Res

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Background Given the additional risk of suicide-related behaviors in adolescents with allergic rhinitis (AR), it is important to use the growing field of machine learning (ML) to evaluate this risk. Objective This study aims to evaluate the validity and usefulness of an ML model for predicting suicide risk in patients with AR. Methods We used data from 2 independent survey studies, Korea Youth Risk Behavior Web-based Survey (KYRBS; n=299,468) for the original data set and Korea National Health and Nutrition Examination Survey (KNHANES; n=833) for the external validation data set, to predict suicide risks of AR in adolescents aged 13 to 18 years, with 3.45% (10,341/299,468) and 1.4% (12/833) of the patients attempting suicide in the KYRBS and KNHANES studies, respectively. The outcome of interest was the suicide attempt risks. We selected various ML-based models with hyperparameter tuning in the discovery and performed an area under the receiver operating characteristic curve (AUROC) analysis in the train, test, and external validation data. Results The study data set included 299,468 (KYRBS; original data set) and 833 (KNHANES; external validation data set) patients with AR recruited between 2005 and 2022. The best-performing ML model was the random forest model with a mean AUROC of 84.12% (95% CI 83.98%-84.27%) in the original data set. Applying this result to the external validation data set revealed the best performance among the models, with an AUROC of 89.87% (sensitivity 83.33%, specificity 82.58%, accuracy 82.59%, and balanced accuracy 82.96%). While looking at feature importance, the 5 most important features in predicting suicide attempts in adolescent patients with AR are depression, stress status, academic achievement, age, and alcohol consumption. Conclusions This study emphasizes the potential of ML models in predicting suicide risks in patients with AR, encouraging further application of these models in other conditions to enhance adolescent health and decrease suicide rates.

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Global Incidence and Prevalence of Chronic Rhinosinusitis: A Systematic Review

Min,

Lee,

Kim

et al. 2024

Clin Experimental Allergy

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ObjectiveData on the global prevalence of chronic rhinosinusitis (CRS) is significantly varied and limited across countries and over time. Therefore, we aimed to conduct a comprehensive investigation into the global, regional, and national burden of CRS from the years 1980 to 2021, as well as identify those factors that influence levels of such burden.DesignWe conducted a systematic review and meta‐analysis of general population‐based observational studies focusing on CRS. We calculated pooled estimates of CRS prevalence and incidence with 95% confidence intervals (CIs). Subgroup analyses were conducted stratifying by sex, age cohorts, geographic regions, smoking status, obesity, and comorbid conditions.Data SourcesPubMed/MEDLINE, EMBASE, CINAHL, Google Scholar, and Cochrane databases.Eligibility Criteria for SelectionWe included general population‐based observational studies on CRS published from database inception through October 20, 2023.ResultsA total of 28 eligible studies, encompassing more than 237 million participants and 11,342,923 patients with CRS from 20 countries across four continents, were included in the analysis. Global pooled prevalence of CRS and CRS with nasal polyps (CRSwNP) was found to be 8.71% (95% CI, 6.69–11.33; number of studies, 20) and 0.65% (95% CI, 0.56–0.75; number of studies, 4), respectively. The prevalence of CRS was greater in Europe compared with North America, South America, and Asia; adults compared with children; smokers compared with never‐smoker; those with obesity compared with normal weight; and those with comorbidities such as asthma, diabetes mellitus, eczema, and nasal septal deviation. Pooled prevalence of CRS increased from 1980 to 2020 (1980–2000: 4.72%; 95% CI, 2.12–10.49; 2014–2020: 19.40%; 95% CI, 12.12–31.07). Similar patterns were observed in CRS incidence.ConclusionsOur study provides valuable insights into CRS prevalence and incidence across diverse demographic and clinical factors, highlighting its increasing global burden. The reported prevalence of CRS varies internationally, and may be increasing over time. To enhance data quality and comparability, standardization of reporting methodologies is imperative.Systematic Review RegistrationPROSPERO (registration no. CRD42024527805).

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National Trends in Allergic Rhinitis and Chronic Rhinosinusitis and COVID-19 Pandemic-Related Factors in South Korea, from 1998 to 2021

Cited by 7 publications

References 10 publications

National prevalence of atopic dermatitis in Korean adolescents from 2009 to 2022

National prevalence of atopic dermatitis in Korean adolescents from 2009 to 2022

Machine Learning–Based Prediction of Suicidality in Adolescents With Allergic Rhinitis: Derivation and Validation in 2 Independent Nationwide Cohorts

Global Incidence and Prevalence of Chronic Rhinosinusitis: A Systematic Review

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