Nationwide biopsy survey of renal diseases in the Czech Republic during the years 1994–2011

Abstract

This report provides representative population-based data on native biopsy-proven renal diseases in the Czech Republic. Over the 18 years of nationwide biopsy survey, we noted an increase of the mean age of renal biopsy cases, an increasing proportion of elderly, and a cardinal change in biopsy technique towards ultrasonography needle guidance.

IgA Nephropathy in Czech Patients - Are We Able Reliably Predict the Outcome?

“…These results correspond with higher biopsy rate in Finland (176 p.m.p./year) [14] and in Australia (215 p.m.p./year) [15] and lower biopsy rate in Scotland (126.3 p.m.p./year) [16,17]. The biopsy rate in the Czech Republic increased significantly from 44.1 p.m.p./year in 1994 to 58.2 p.m.p./year in 2001 and to 61.6 p.m.p./year in 2011 [4]. We realize that we used two values of CrCl (initial and final) to calculate slope of CrCl compared to minimal 3 mean values in above mentioned publication [6].…”

“…Diagnosis of IgAN was established by renal biopsy. The details about histological diagnoses of renal biopsies have already been published [2,4]. Written informed consent for renal biopsy and for use of clinical data in this analysis was obtained from all patients and the study was approved by the ethics committee of the General University Hospital in Prague (1443/11 S-IV).…”

Renal Biopsy in 2015 - From Epidemiology to Evidence-Based Indications

“…1 ). In 9 national renal biopsy registries (Scotland, Italy, Spain, Czech Republic, Japan, Brazil, Bahrain, Uruguay, Denmark) [17][18][19][20][21][22][23][24][25][26][27][28], the median total number of biopsies performed was 1,818, ranging from 498 [20] to 14,607 [24] . In data from 6 macro-regional databases (France, Finland, Romania, Australia, North Germany, West Saudi Arabia) [29][30][31][32][33][34][35] and 12 single-center reports [36][37][38][39][40][41][42][43][44][45][46][47] , the overall number of biopsies ranged from 251 [29] to 3,310 [34] .…”

“…As shown in table 3 and figures 2-4 , IgAN represents the most frequent primary, biopsy-proven GN in 6 out of 8 national registries (Italy, Spain, Czech Republic, Denmark, Scotland, Japan) [17,19,[22][23][24][25][26][27][28] , in 3 macroregional (Western France, Finland, Victoria-Australia) [30,32,34] and 7 single-center databases [36,39,40,42,44,45,47] with a percentage of total diagnoses ranging from 12.6% [44] to 45% [45] . Focal segmental glomerulosclerosis (FSGS) was the most frequent primary GN in Brazil (24.6%) [18] , in the Uruguayan registry of glomerulopathies [21] (29.3%) and in Bahrain (23.8%) [20,35] .…”

“…Urinary abnormalities (such as microhematuria or non-nephrotic proteinuria) emerged as the most common reasons for performing renal biopsy in 2 national registries [22,24,28] , in 2 macro-regional reports [31,34] and in a single-center database [47] .…”