Nationwide database analysis of insomnia, depression, and sleeping pill prescriptions in hepatocellular carcinoma patients

Akada, Keishi; Koyama, Noriyuki; Miura, Yuji; Aoshima, Ken

doi:10.1080/03007995.2022.2081451

Cited by 3 publications

(1 citation statement)

References 51 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Previous studies show that MDT improves QoL of many patients with cancers (18-20, 29), however, the effect of MDT on QoL in HCC patients after surgery is unclear. Our results illustrated that MDT-CP elevated QoL of HCC patients who underwent surgery, especially in terms of global health status and functions, which might be because MDT-CP made a HCC patients who underwent surgery have a high incidence of anxiety and depression (30,31). One study shows that about 48% of HCC patients who underwent surgery experienced anxiety and about 18% experienced depression (32).…”

Section: Discussionmentioning

confidence: 68%

Effect of multi-disciplinary team care program on quality of life, anxiety, and depression in hepatocellular carcinoma patients after surgery: A randomized, controlled study

Yang

Yan²,

Wang³

2023

Front. Surg.

View full text Add to dashboard Cite

ObjectiveMulti-disciplinary team (MDT) collaboration enables hepatocellular carcinoma (HCC) patients to achieve better survival through precise diagnosis and individualized treatment. This study aimed to further investigate the effect of MDT care program (MDT-CP) on quality of life (QoL), anxiety and depression in HCC patients after surgery.MethodsTotally, 150 postoperative HCC patients were enrolled and randomized in a 1:1 ratio into the MDT-CP group (N = 76) to receive MDT care for 6 months and the normal care program (N-CP) group (N = 74) to receive routine care for 6 months.ResultsQuality of Life Questionnaire-Core 30 (QLQ-C30) global health status score at 1 month (M1), M3 and M6, QLQ-C30 functions score at M3 and M6 elevated while QLQ-C30 symptom score at M1 and M3 decreased in MDT-CP group compared with N-CP group (all P < 0.05). In addition, Hospital Anxiety and Depression Scale (HADS)-Anxiety score at M3 and M6, anxiety occurrence rate at M6, anxiety degree at M6, were all reduced in MDT-CP group compared with N-CP group (all P < 0.05). HADS-Depression score at M6, and depression occurrence rate at M3, were both lessened in MDT-CP group compared to N-CP group (both P < 0.05), while there was no distinction of depression degree at any time points between groups.ConclusionMDT-CP improves QoL, relieves anxiety and depression to a certain extent in HCC patients after surgery.

show abstract

Section: Discussionmentioning

confidence: 68%

Effect of multi-disciplinary team care program on quality of life, anxiety, and depression in hepatocellular carcinoma patients after surgery: A randomized, controlled study

Yang

Yan²,

Wang³

2023

Front. Surg.

View full text Add to dashboard Cite

show abstract

Sedative-hypnotics and osteoporotic fractures: A systematic review of observational studies with over six million individuals

Xu,

Leung,

Shi

et al. 2024

Sleep Medicine Reviews

View full text Add to dashboard Cite

Depression and anxiety management in cirrhosis

Zimbrean,

Jakab

2024

Hepatology Communications

View full text Add to dashboard Cite

Depressive and anxiety symptoms are more prevalent in patients with cirrhosis compared to the general population. Between 2009 and 2019, the prevalence of depression in cirrhosis increased by 80%, while the prevalence of generalized anxiety disorder increased by over 400%. When present, anxiety and depression are linked to lower health-related quality of life, more severe symptoms (eg, fatigue), and poorer response to medical treatment. Screening instruments for depression and anxiety have shown acceptable validity in patients with cirrhosis. However, the diagnosis of depression and anxiety disorder remains challenging in this population and should follow the established criteria for general populations. Treatment interventions are numerous and include patient education and support around liver disease, pharmacological agents, and psychotherapy. Antidepressants are the treatment of choice for patients with depressive or anxiety disorder and cirrhosis. However, consideration must be given to dose adjustment and choice of agent due to changes in their metabolism in patients with liver disease. Psychotherapy may be used as a stand-alone therapy or concomitantly with pharmacotherapy. The high prevalence and complexity of depressive and anxiety symptoms in patients with cirrhosis support the integrated care approach in which patients are cared for by multidisciplinary teams.

show abstract

Nationwide database analysis of insomnia, depression, and sleeping pill prescriptions in hepatocellular carcinoma patients

Cited by 3 publications

References 51 publications

Effect of multi-disciplinary team care program on quality of life, anxiety, and depression in hepatocellular carcinoma patients after surgery: A randomized, controlled study

Effect of multi-disciplinary team care program on quality of life, anxiety, and depression in hepatocellular carcinoma patients after surgery: A randomized, controlled study

Sedative-hypnotics and osteoporotic fractures: A systematic review of observational studies with over six million individuals

Depression and anxiety management in cirrhosis

Contact Info

Product

Resources

About