Native Tissue Harmonic Imaging Improves Endocardial Border Definition and Visualization of Cardiac Structures

Kornbluth, Murray; Liang, David; Paloma, Allan; Schnittger, Ingela

doi:10.1053/je.1998.v11.a90474

Cited by 123 publications

(56 citation statements)

References 7 publications

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“…Tissue harmonic imaging enhances EBD in patients with poor acoustic windows. 3,19 The intensity of the generated second harmonic signal is proportional to the distance from the transducer, so a stronger signal will come back from the basal to mid LV than from the apical LV, 1 which is what we found in this study. Fundamental imaging with Levovist showed better apical endocardial delineation than did tissue harmonic imaging, probably because the generation of native second harmonic frequency in the near field may be insufficient, even though near field artefacts are suppressed.…”

Section: Tissue Harmonic Imaging Vs Fundamental Imaging With Levovistsupporting

confidence: 78%

“…1,2 With the advent of tissue harmonic imaging, that percentage has fallen, but 5-10% of cases still have suboptimal results. 1,3 The introduction of transpulmonary contrast agents has further reduced the number of suboptimal cases 1,4 and are useful for endocardial border delineation (EBD) at rest and during stress echocardiography. 1,[4][5][6][7][8] From September 1999, an-air-filled contrast agent, Levovist, became commercially available in Japan for LV border delineation and myocardial perfusion.…”

mentioning

confidence: 99%

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Head-to-Head Comparison of Fundamental, Tissue Harmonic and Contrast Harmonic Imaging With or Without an Air-Filled Contrast Agent, Levovist, for Endocardial Border Delineation in Patients With Poor Quality Images.

Yoshitani

Takeuchi

Hirose

et al. 2002

Circ J

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Section: Tissue Harmonic Imaging Vs Fundamental Imaging With Levovistsupporting

confidence: 78%

mentioning

confidence: 99%

Head-to-Head Comparison of Fundamental, Tissue Harmonic and Contrast Harmonic Imaging With or Without an Air-Filled Contrast Agent, Levovist, for Endocardial Border Delineation in Patients With Poor Quality Images.

Yoshitani

Takeuchi

Hirose

et al. 2002

Circ J

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“…New techniques such as tissue Doppler, the development in second harmonic imaging and the use of contrast agents have improved the diagnostic accuracy of the method [45].…”

Section: Progress In Echocardiographic Stress Testsmentioning

confidence: 99%

<![CDATA[<b>Stress echocardiography in coronary artery disease</b>]]>

Oliveira¹,

Barreto²,

Silva³

et al. 2004

Braz. j. cardiovasc. surg.

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Doppler echocardiography is a simple, fast and noninvasive method to identify abnormal regional or global left ventricular function. One could consider this non-invasive method to be the best approach of all imaging techniques.Stress echocardiography techniques are used for the diagnosis, risk stratification, prognosis and the study of myocardial viability in ischemic heart disease. There are many ways of subjecting the heart to stress for echocardiographic studies. For physically fit patients exercise stress testing using a treadmill or bicycle is employed and patients who are unable to exercise undergo pharmacological tests.Although accurate diagnosis and a high prognostic value are achieved with both methods, there are new techniques under study, including the utilization of echocardiographic microbubble contrast for endocardial edge evaluation and for myocardial perfusion studies. Descriptors: Stress. Echocardiography. Coronary disease.Resumo A ecodopplercardiografia é uma metodologia simples, rápida e não invasiva para identificar anormalidades regional e global da função do ventrículo esquerdo, podendo ser considerado o método não invasivo de maior aplicabilidade dentro das técnicas de imagem.A ecocardiografia sob estresse é utilizada para diagnóstico, estratificação de risco, prognóstico e avaliação da viabilidade miocárdica na doença arterial coronariana. Várias são as formas de se submeter o coração ao estresse para o estudo ecocardiográfico. Para indivíduos com capacidade física preservada, utiliza-se o teste com esteira ou bicicleta e para aqueles sem condições de se exercitar, são usados os testes farmacológicos.Apesar da boa acurácia diagnóstica e do valor prognóstico com os dois métodos já referidos, novas técnicas vêm sendo estudadas, como a utilização do contraste ecocardiográfico com microbolhas para avaliação das bordas do endocárdio e o estudo da perfusão miocárdica.Descritores: Estresse. Ecocardiografia. Coronariopatia. 56OLIVEIRA, JLM ET AL -Stress echocardiography in coronary artery disease Rev

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“…To overcome this inferiority for imaging, many new techniques for enhancing bubble signals have being developed. They utilize the unique scattering behavior of microbubbles when they are exposed to ultrasound, such as second harmonic (2H) imaging [1,2], intermittent imaging [3][4][5], pulse inversion imaging [6], sub-harmonic imaging [7], power modulation [8], power pulse-inversion imaging [9,10], power Doppler imaging [11,12] and ultraharmonic imaging [13]. By using these techniques, the echo signal of bubbles can be separated from that of tissues.…”

Section: Introductionmentioning

confidence: 99%

Efficacy of 1.5 Harmonic Imaging for Intravenous Myocardial Contrast Echocardiography

et al. 2005

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Background. Although second harmonic (2H) imaging is utilized to minimize the tissue signals in myocardial contrast echocardiography (MCE), the native tissue harmonic signal is sufficiently high enough to cause a misreading of myocardial opacification when high mechanical index (MI) is used.Purpose. The backscattered signal from microbubbles at high MI is broadband, while it is narrowband at low MI.Therefore, the bubble/tissue signal ratio is expected to be high between the fundamental signal and 2H frequencies at high MI. Our aim was to elucidate the efficacy of a new imaging method using an in-between frequency, denoted as 1.5 harmonic (1.5H) imaging.Methods. Six open-chest dogs were examined using Toshiba APLIO with 1.5H and conventional 2H system. The transmitting/receiving frequencies were 2.3/3.3 MHz for 1.5H and 1.4/2.8MHz for 2H imaging, respectively.Intermittent MCE was performed at a MI of 1.6 after injection of Levovist , and baseline intensity and peak intensity of opacification of the ventricular septum were measured.Results. While baseline intensity of the septum was significantly lower using 1.5H than 2H (26 4 vs. 43 14 gray level, p<0.001), the opacification after Levovist was significantly higher using 1.5H than 2H (91 32 vs. 51 38, p<0.001). Due to the combination of these effects, visual recognition of myocardial opacification was quite superior with 1.5H imaging.Conclusion. The 1.5H imaging system provides superb contrast opacification when using high MI. (J Echocardiogr 2005; 3: 104-108)

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Native Tissue Harmonic Imaging Improves Endocardial Border Definition and Visualization of Cardiac Structures

Cited by 123 publications

References 7 publications

Head-to-Head Comparison of Fundamental, Tissue Harmonic and Contrast Harmonic Imaging With or Without an Air-Filled Contrast Agent, Levovist, for Endocardial Border Delineation in Patients With Poor Quality Images.

Head-to-Head Comparison of Fundamental, Tissue Harmonic and Contrast Harmonic Imaging With or Without an Air-Filled Contrast Agent, Levovist, for Endocardial Border Delineation in Patients With Poor Quality Images.

<![CDATA[<b>Stress echocardiography in coronary artery disease</b>]]>

Efficacy of 1.5 Harmonic Imaging for Intravenous Myocardial Contrast Echocardiography

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