The solute-nanostructures formed in the primary α-Al grains of a Semi-Solid Metal cast Al-7Si-0.6Mg alloy (F357) during ageing at 180°C, and the age-hardening response of the alloy have been systematically investigated using transmission electron microscopy, atom probe tomography and hardness testing. A 120-h natural pre-ageing led to the formation of solute clusters and GP zones. The natural pre-ageing slowed down the precipitation kinetics six-fold during 1 h ageing at 180°C, but this effect diminished after 4 h when the sample reached the same hardness as that without the pre-ageing treatment. It reduced the number density of β″-needles to approximately half of that formed in samples without the treatment, and postponed the peak hardness occurrence to 4 h, 4 times that of the as-quenched sample. A hardness plateau developed in the as-quenched sample between 1 h and 4 h ageing corresponds to the growth of 2 the β″ precipitates and a significant concurrent decrease of solute clusters and GP zones. The average Mg:Si ratio of early solute clusters is < 0.7 while that of GP zones changes from 0.8 to 0.9 with increasing in their size, and that of β″-needles increases from 0.9 to 1.2. β″-needles, GP zones and solute clusters are important strengthening solute nanostructures of the alloy. The partitioning of solutes and precipitation kinetics of the alloy are discussed in detail.