NATURAL ANTIOXIDANTS IN HENS' EMBRYOGENESIS AND ANTISTRESS DEFENCE IN POSTNATAL DEVELOPMENT (review)

Surai, Peter F.; Фисинин, В.И.

doi:10.15389/agrobiology.2013.2.3eng

Cited by 14 publications

(16 citation statements)

References 49 publications

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“…Vaccinations [70][71][72] Microbial or virus challenges [73][74][75][76][77][78] Gut dis-bacteriosis [79][80][81][82][83] Pipping and hatching [5,84,85] A growing body of evidence clearly indicates that oxidative stress is involved in most of commercially relevant stresses in poultry production (for review see [1,2,15,60,86]).…”

Section: Internal Stressorsmentioning

confidence: 99%

Antioxidant Defence Systems and Oxidative Stress in Poultry Biology: An Update

et al. 2019

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Poultry in commercial settings are exposed to a range of stressors. A growing body of information clearly indicates that excess ROS/RNS production and oxidative stress are major detrimental consequences of the most common commercial stressors in poultry production. During evolution, antioxidant defence systems were developed in poultry to survive in an oxygenated atmosphere. They include a complex network of internally synthesised (e.g., antioxidant enzymes, (glutathione) GSH, (coenzyme Q) CoQ) and externally supplied (vitamin E, carotenoids, etc.) antioxidants. In fact, all antioxidants in the body work cooperatively as a team to maintain optimal redox balance in the cell/body. This balance is a key element in providing the necessary conditions for cell signalling, a vital process for regulation of the expression of various genes, stress adaptation and homeostasis maintenance in the body. Since ROS/RNS are considered to be important signalling molecules, their concentration is strictly regulated by the antioxidant defence network in conjunction with various transcription factors and vitagenes. In fact, activation of vitagenes via such transcription factors as Nrf2 leads to an additional synthesis of an array of protective molecules which can deal with increased ROS/RNS production. Therefore, it is a challenging task to develop a system of optimal antioxidant supplementation to help growing/productive birds maintain effective antioxidant defences and redox balance in the body. On the one hand, antioxidants, such as vitamin E, or minerals (e.g., Se, Mn, Cu and Zn) are a compulsory part of the commercial pre-mixes for poultry, and, in most cases, are adequate to meet the physiological requirements in these elements. On the other hand, due to the aforementioned commercially relevant stressors, there is a need for additional support for the antioxidant system in poultry. This new direction in improving antioxidant defences for poultry in stress conditions is related to an opportunity to activate a range of vitagenes (via Nrf2-related mechanisms: superoxide dismutase, SOD; heme oxygenase-1, HO-1; GSH and thioredoxin, or other mechanisms: Heat shock protein (HSP)/heat shock factor (HSP), sirtuins, etc.) to maximise internal AO protection and redox balance maintenance. Therefore, the development of vitagene-regulating nutritional supplements is on the agenda of many commercial companies worldwide.

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Section: Internal Stressorsmentioning

confidence: 99%

Antioxidant Defence Systems and Oxidative Stress in Poultry Biology: An Update

et al. 2019

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“…We chose to expose offspring to paraquat acutely in order to mimic naturally occurring transient stressors such as harsh climatic conditions or acute pathogen infections, which are known to increase offspring oxidative stress (Beaulieu, Haas, & Schaefer, 2014;Marri & Richner, 2015). Given that offspring mostly rely on maternal antioxidants for a few days after hatching (Giordano, Costantini, & Tschirren, 2015;Parolini et al, 2017;Surai & Fisinin, 2013), we exposed offspring to paraquat at the specific age of 11 days old such that the observed treatment effects primarily reflected the offspring's own physiological response. We used paraquat, the active molecule of a widely used herbicide, because it is well known to increase OS in animals through increased reactive species production (Koch & Hill, 2017).…”

Section: Methodsmentioning

confidence: 99%

Effects of an early‐life paraquat exposure on adult resistance to oxidative stress, plumage colour and sperm performance in a wild bird

Losdat

Blount

Marri

et al. 2018

Journal of Animal Ecology

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Early-life stressful conditions can shape individual phenotypes and ultimately influence fitness. Oxidative stress is a pervasive threat that affects many fitness-related traits and can modulate life-history trade-offs. Yet, the extent to which exposure to oxidative stress during early life can have long-lasting effects on key fitness-related traits remains to be elucidated, particularly in natural populations of vertebrates. Using a wild population of great tits Parus major, we experimentally dosed 11-day-old birds with paraquat, a pro-oxidant molecule, aiming at increasing oxidative stress. One year later, we recaptured 39 of them as adult recruiting breeders and quantified effects of the paraquat exposure on their resistance to oxidative stress, carotenoid-based plumage coloration and male sperm performance. Despite the absence of a short-term effect of paraquat on oxidative stress measured two days later, the pre-fledging exposure to paraquat induced a reduction in individual oxidative damage measured at adulthood. Paraquat-dosed individuals also had brighter plumage, but no effect was observed on male sperm performance. For the first time in a natural population of vertebrates, we experimentally show that an early-life acute exposure to a pro-oxidant has long-lasting effects on individual resistance to oxidative stress at adulthood. Our results are in line with the environmental matching and the hormesis hypotheses but may also reflect selective disappearance of individuals with lower resistance to oxidative stress.

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“…Given the relatively high temperature and humidity in the hatcher, it is possible to make the argument that the chick may be under chronic oxidative stress during this holding time [23,47]. Therefore, antioxidant protection at hatching time is considered to be an important determinant of chick viability during first posthatch days [3,[48][49][50]. During chick embryo development there is an antioxidant/prooxidant balance in the tissues which supports normal embryonic development and post-hatch chick viability [48][49][50][51].…”

Section: Economics (In Roubles) Of Arbor Acres Broiler Meat Productiomentioning

confidence: 99%

Vitagene Regulation as a New Strategy to Fight Stresses in Poultry Production

Grigorieva¹,

Velichko²,

Shabaldin³

et al. 2017

S-h. biol.

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A b s t r a c tCommercial poultry production is associated with various stresses leading to decrease of productive and reproductive performance of growing chickens, parent birds and layers. In commercial poultry/animal production, there are four major types of stress: technological, environmental, nutritional and internal stresses. A growing body of evidence indicates that most of the stresses in poultry production at the cellular level are associated with oxidative stress due to excess of free radical production or inadequate antioxidant protection. The vitagene concept of fighting stresses emerged as a new direction in a nutritional research and it was successfully transferred from medical sciences to agricultural sciences, including poultry and pig production. In fact, vitagene regulation by nutritional means appeared as a new approach to realise a full potential of the body for adaptation to stress conditions in poultry/animal production. Therefore, the aim of the study was to test if supplementation of the vitagene-regulating antioxidant mixture (Magic Antistress Mix/PerforMax) with drinking water can improve broiler performance in stressful conditions of commercial chicken production. The experiment was conducted at the poultry farm AO «Prodo Tumenskiy Broiler» (Tumen region, Russia) in a special poultry house designed and equipped for conducting experimental trials and measuring growth parameters weekly. Twelve thousand and four hundred newly hatched Arbor Acres chicks were divided into two equal groups with four replicates in each group and placed in poultry house. The results confirmed the idea that using vitagene-regulating mixture with drinking water can improve chicken performance, including improvement in FCR (1.50 vs 1.56 in control) and vaccination efficacy, as shown by increased vaccination index by 40 %).Commercial poultry production is associated with various stresses leading to decrease of productive and reproductive performance of growing chickens, parent birds and layers. Indeed, domestication and genetic selection based on rapid growth rates, improved feed conversion, and heavier body weight (BW) of broilers has made domestic birds, including broilers and turkeys, particularly susceptible to oxidative stress [1]. From a physiological point of view, stress is related to a deviation from optimal internal and external conditions. Under stressful conditions, the hypothalamic-pituitary-adrenal axis, the autonomic nervous system and the immune system are responsible for re-establishing homeostasis. Therefore, a cascade of regulatory mechanisms is involved, resulting in a mobilisation of energy and a shift in metabolism, with detrimental effects on growth

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NATURAL ANTIOXIDANTS IN HENS' EMBRYOGENESIS AND ANTISTRESS DEFENCE IN POSTNATAL DEVELOPMENT (review)

Cited by 14 publications

References 49 publications

Antioxidant Defence Systems and Oxidative Stress in Poultry Biology: An Update

Antioxidant Defence Systems and Oxidative Stress in Poultry Biology: An Update

Effects of an early‐life paraquat exposure on adult resistance to oxidative stress, plumage colour and sperm performance in a wild bird

Vitagene Regulation as a New Strategy to Fight Stresses in Poultry Production

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