Natural Dietary and Herbal Products in Anti-Obesity Treatment

Sun, Nan-Nong; Wu, Tsung-Yen; Chau, Chi‐Fai

doi:10.3390/molecules21101351

Cited by 182 publications

(137 citation statements)

References 74 publications

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“…There are various pharmacological and non-pharmacological options which are broadly accepted as treatment and prevention of obesity and obesity-related diseases, including dietary control, physical activity, lifestyle changes, weight-loss medications, weight-loss surgeries, or specific medications [13]. Various dietary patterns have been extensively studied for health promotion and to diminish the risks of chronic diseases.…”

Section: Introductionmentioning

confidence: 99%

Morinda citrifolia Linn. (Noni) and Its Potential in Obesity-Related Metabolic Dysfunction

et al. 2017

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Cultural and economic shifts in the early 19th century led to the rapid development of companies that made good profits from technologically-produced commodities. In this way, some habits changed in society, such as the overconsumption of processed and micronutrient-poor foods and devices that gave rise to a sedentary lifestyle. These factors influenced host-microbiome interactions which, in turn, mediated the etiopathogenesis of “new-era” disorders and diseases, which are closely related, such as obesity, type 2 diabetes mellitus, non-alcoholic fatty liver disease, hypertension, and inflammatory bowel disease, which are characterized by chronic dysregulation of metabolic and immune processes. These pathological conditions require novel and effective therapeutic approaches. Morinda citrifolia (noni) is well known as a traditional healing plant due to its medicinal properties. Thus, many studies have been conducted to understand its bioactive compounds and their mechanisms of action. However, in obesity and obesity-related metabolic (dysfunction) syndrome, other studies are necessary to better elucidate noni’s mechanisms of action, mainly due to the complexity of the pathophysiology of obesity and its metabolic dysfunction. In this review, we summarize not only the clinical effects, but also important cell signaling pathways in in vivo and in vitro assays of potent bioactive compounds present in the noni plant which have been reported in studies of obesity and obesity-associated metabolic dysfunction.

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Section: Introductionmentioning

confidence: 99%

Morinda citrifolia Linn. (Noni) and Its Potential in Obesity-Related Metabolic Dysfunction

et al. 2017

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“…This goes to support the fact that even lean people with less fat mass grower's mash specially prepared for the growth of poulets that are of commercial use. Diets deficient in protein often increase food consumption, body weight and fat mass [26][27][28][29][30]; however, the underlying mechanisms remain poorly understood of the underlying mechanisms by which moderate protein deficiency…”

Section: Discussionmentioning

confidence: 99%

Dietary Factors in Fasting Blood Glucose Levels and Weight Gain in Female Sprague Dawley Rats

Samuel¹,

Samuel²,

Donatus³

et al. 2017

J Clin Nutr Diet

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“…The quest for and application of bioactive extracts and purified chemical substances of nutritional interest from both herbal and animal origin is attracting increasing attention among clinical and basic science investigators (e.g., [19, 93]).…”

Section: Guidelines Standards and Reproducibility Of Scientific Datmentioning

confidence: 99%

Propelling the paradigm shift from reductionism to systems nutrition

Kaput

Perozzi²,

Radonjić³

et al. 2017

Genes Nutr

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The complex physiology of living organisms represents a challenge for mechanistic understanding of the action of dietary bioactives in the human body and of their possible role in health and disease. Animal, cell, and microbial models have been extensively used to address questions that could not be pursued experimentally in humans, posing an additional level of complexity in translation of the results to healthy and diseased metabolism. The past few decades have witnessed a surge in development of increasingly sensitive molecular techniques and bioinformatic tools for storing, managing, and analyzing increasingly large datasets. Application of such powerful means to molecular nutrition research led to a major leap in study designs and experimental approaches yielding experimental data connecting dietary components to human health. Scientific journals bear major responsibilities in the advancement of science. As primary actors of dissemination to the scientific community, journals can impose rigid criteria for publishing only sound, reliable, and reproducible data. Journal policies are meant to guide potential authors to adopt the most updated standardization guidelines and shared best practices. Such policies evolve in parallel with the evolution of novel approaches and emerging challenges and therefore require constant updating. We highlight in this manuscript the major scientific issues that led to formulating new, updated journal policies for Genes & Nutrition, a journal which targets the growing field of nutritional systems biology interfacing personalized nutrition and preventive medicine, with the ultimate goal of promoting health and preventing or treating disease. We focus here on relevant issues requiring standardization in nutrition research. We also introduce new sections on human genetic variation and nutritional bioinformatics which follow the evolution of nutritional science into the twenty-first century.

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Natural Dietary and Herbal Products in Anti-Obesity Treatment

Cited by 182 publications

References 74 publications

Morinda citrifolia Linn. (Noni) and Its Potential in Obesity-Related Metabolic Dysfunction

Morinda citrifolia Linn. (Noni) and Its Potential in Obesity-Related Metabolic Dysfunction

Dietary Factors in Fasting Blood Glucose Levels and Weight Gain in Female Sprague Dawley Rats

Propelling the paradigm shift from reductionism to systems nutrition

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