1993
DOI: 10.1002/jmv.1890410506
|View full text |Cite
|
Sign up to set email alerts
|

Natural history, management and complications of herpes labialis

Abstract: Infection with herpes simplex virus (HSV) is a common worldwide problem. Primary infection with HSV-1 rarely causes significant problems although widespread involvement in atopic eczema can be life-threatening as may associated encephalitis. Keratoconjunctivitis, pharyngitis and hepatitis can also complicate primary infection. Twenty to 40% of the population at some stage have recurrent orolabial infections with HSV although in only 1% of these cases is this recurrence severe. Recurrent erythema multiforme app… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1

Citation Types

1
48
0
9

Year Published

2002
2002
2022
2022

Publication Types

Select...
8
2

Relationship

0
10

Authors

Journals

citations
Cited by 63 publications
(58 citation statements)
references
References 37 publications
1
48
0
9
Order By: Relevance
“…However, these viruses can reemerge from latency to cause disease in up to 30% of the population (Higgins et al, 1993;Kilkenny and Marks, 1996;Harpaz et al, 2008). In contrast to normal individuals, DOCK8-deficient patients with autosomalrecessive loss-of-function mutations in DOCK8 have impaired cellular and humoral immunity (Engelhardt et al, 2009;Zhang et al, 2009;Su et al, 2011;Jing et al, 2014) that manifests as extreme susceptibility to skin and other infections (Chu et al, 2012).…”
mentioning
confidence: 99%
“…However, these viruses can reemerge from latency to cause disease in up to 30% of the population (Higgins et al, 1993;Kilkenny and Marks, 1996;Harpaz et al, 2008). In contrast to normal individuals, DOCK8-deficient patients with autosomalrecessive loss-of-function mutations in DOCK8 have impaired cellular and humoral immunity (Engelhardt et al, 2009;Zhang et al, 2009;Su et al, 2011;Jing et al, 2014) that manifests as extreme susceptibility to skin and other infections (Chu et al, 2012).…”
mentioning
confidence: 99%
“…Despite the presence of HSV-reactive T cells, HSV causes substantial human morbidity. The seroprevalence rate of HSV-1 in the United States approaches 90% in certain populations (4), and HSV-2 is the leading cause of genital ulcers worldwide (5). Onethird of those infected with HSV experience recurrent, painful mucocutaneous ulcers as a result of viral reactivation (6).…”
mentioning
confidence: 99%
“…After about 24 hours lesions appear and characterized by erythema, papules and blisters. The lesions crust over and heal without scarring over a period of 1-2 weeks [5]. The diagnosis of RHL is based on the history, classic location and clinical appearance of the lesions [6].…”
Section: Introductionmentioning
confidence: 99%