Natural History of Common Autologous Arteriovenous Fistulae: Consequences for Planning of Dialysis Access

Wilmink, Teun; Hollingworth, Lee; Powers, Sarah; Allen, Clive; Dasgupta, Indranil

doi:10.1016/j.ejvs.2015.10.005

Cited by 74 publications

(82 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Functional dialysis use (FDU) was defined as six consecutive dialysis sessions with two needles on the AVF. 24,25 Primary failure (PF) was defined as failure to achieve six consecutive successful two needle cannulations of the AVF. This included failure to mature.…”

Section: Methodsmentioning

confidence: 99%

“…The authors' standardised assessment protocol has been described previously. 6,8,24 Pulses at elbows and wrists, and the superficial veins in the forearm and upper arm (with tourniquet) were assessed clinically by one of three vascular surgeons or a vascular access nurse specialist. This was followed by ultrasound examination by the same assessor in the same clinic.…”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Diameter Criteria Have Limited Value for Prediction of Functional Dialysis Use of Arteriovenous Fistulas

Wilmink

Houlihan

2018

European Journal of Vascular and Endovascular Surgery

View full text Add to dashboard Cite

show abstract

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Diameter Criteria Have Limited Value for Prediction of Functional Dialysis Use of Arteriovenous Fistulas

Wilmink

Houlihan

2018

European Journal of Vascular and Endovascular Surgery

View full text Add to dashboard Cite

show abstract

“…dilate and thicken. Unfortunately, AVF have a high rate of primary maturation failure with up to 60% not suitable for HD by 5 months after creation [19–22]. Furthermore, a recent systematic review and meta-analysis reported that the primary patency rates of AVF were 60% at 1 year and 51% at 2 years, with secondary patency rates of 71% at 1 year and 64% at 2 years, clearly suboptimal for a permanent treatment [23].…”

Section: Introductionmentioning

confidence: 99%

Future research directions to improve fistula maturation and reduce access failure

Patel

Hänisch

et al. 2016

Seminars in Vascular Surgery

View full text Add to dashboard Cite

With the increasing prevalence of end stage renal disease there is a growing need for hemodialysis. Arteriovenous fistulae (AVF) are the preferred type of vascular access for hemodialysis but maturation and failure continue to present significant barriers to successful fistula use. AVF maturation integrates outward remodeling with vessel wall thickening in response to drastic hemodynamic changes, in the setting of uremia, systemic inflammation, oxidative stress and preexistent vascular pathology. AVF can fail due to both failure to mature adequately to support hemodialysis, as well as development of neointimal hyperplasia (NIH) that narrows the AVF lumen, typically near the fistula anastomosis. Failure due to NIH involves vascular cell activation and migration and extracellular matrix remodeling with complex interactions of growth factors, adhesion molecules, inflammatory mediators, and chemokines, all of which result in maladaptive remodeling. Different strategies have been proposed to prevent and treat AVF failure, based on current understanding of the modes and pathology of access failure; these approaches range from appropriate patient selection and use of alternative surgical strategies for fistula creation, to the use of novel interventional techniques or drugs to treat failing fistulae. Effective treatments to prevent or treat AVF failure requires a multidisciplinary approach involving nephrologists, vascular surgeons and interventional radiologists, allowing careful patient selection and the use of tailored systemic or localized interventions to improve patient-specific outcomes. This review provides contemporary information on the underlying mechanisms of AVF maturation and failure and discusses the broad spectrum of options that can be tailored for specific therapy.

show abstract

“…Reported rate extending between 24 and 60% rate of failure to mature in studies from European and American hemodialysis patients respectively [6][7][8][9] .…”

Section: Introductionmentioning

confidence: 99%

Role of Balloon Angioplasty in Non-mature Arteriovenous Fistula caused by Stenosis

Ibrahim

2019

International Journal of Medical Arts

View full text Add to dashboard Cite

Background: Arteriovenous fistula (AVF) is a significant procedure for patients in need for hemodialysis. Failure of maturation due to stenosis is a challenge, which need further intervention. Aim of the work: To present our experience in therapeutic intervention for non-mature arteriovenous fistula caused by stenosis using balloon angioplasty. Patients and Methods: 25 patients who had stenosis of primary AVF were included. The mean age was 57.28±6.97 years and patients were 16 males and 9 females. Patients were Followed-up every three months up to 1 year. Collected data included patient demographics, cause of renal failure, characters of primary AVF, and variables of balloon angioplasty (e.g., clinical success and complications), primary patency and recurrence of stenosis. Results: AVF type was radiocephalic (60.0%), brachiobasilic (24.0%) and brachiocephalic (16.0%). The fistula segment was juxta-anastomotic (44%), anastomosis (36.0%) and efferent in 20.0%. Technical success was 100%; the patency rate at 6 months was 80.0%, at 9 months was 64.0% and at 12 months was 56.0%. There was puncture site hematoma in 2 patients (8.0%) that were treated conservatively. The recurrence was reported in 9 patients (36.0%) (8 cases due to reocclusion and one patient due to thrombus formation). Recurrence was significantly associated with older age and high coronary artery disease. Conclusions: Balloon angioplasty is effective and safe procedure for treatment of AVF non-maturation due to stenosis.

show abstract

Natural History of Common Autologous Arteriovenous Fistulae: Consequences for Planning of Dialysis Access

Abstract: RCAVFs have higher PF, but better survival than other AVF, and result in more dialysis time. AVF created pre-dialysis have better survival. An average maturation time of 10 weeks should be considered if planning to start dialysis on an AVF.

Cited by 74 publications

References 24 publications

Diameter Criteria Have Limited Value for Prediction of Functional Dialysis Use of Arteriovenous Fistulas

Diameter Criteria Have Limited Value for Prediction of Functional Dialysis Use of Arteriovenous Fistulas

Future research directions to improve fistula maturation and reduce access failure

Role of Balloon Angioplasty in Non-mature Arteriovenous Fistula caused by Stenosis

Contact Info

Product

Resources

About