Natural history of prostatism: Impact of urinary symptoms on quality of life in 2115 randomly selected community men

Girman, Cynthia J.; Epstein, Robert S.; Jacobsen, Steven J.; Guess, Harry A.; Panser, Laurel A.; Öesterling, Joseph E.; Lieber, Michael M.

doi:10.1016/s0090-4295(94)80165-7

Cited by 130 publications

(75 citation statements)

References 20 publications

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“…18 A number of studies using these tools have documented that LUTS can have a significant impact on quality of life in men with BPH, resulting in increased levels of bother and worry as well as interference with daily activities. [19][20][21][22] Men with moderate to severe symptoms have reported four to six times the degree of bother and interference with daily activities and twice the level of worry as men with mild symptoms. 19 Severe BPH symptoms have been shown to correlate with serious worries and concerns about the urinary condition.…”

Section: Components Of Quality Of Life In Bphmentioning

confidence: 99%

“…[19][20][21][22] Men with moderate to severe symptoms have reported four to six times the degree of bother and interference with daily activities and twice the level of worry as men with mild symptoms. 19 Severe BPH symptoms have been shown to correlate with serious worries and concerns about the urinary condition. 22 Among the more serious urinary conditions that significantly affect quality of life in patients with BPH are bladder stones, urinary retention, urinary tract infection, and renal failure.…”

Section: Components Of Quality Of Life In Bphmentioning

confidence: 99%

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Medical therapy for benign prostatic hyperplasia: sexual dysfunction and impact on quality of life

Carbone

Hodges

2003

Int J Impot Res

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Therapies for benign prostatic hyperplasia (BPH) may either improve or exacerbate sexual function with an ensuing impact on quality of life. Here we review a total of 73 papers on medical therapies for BPH with a focus on the effects of different pharmacological agents on sexual function. For example, certain a 1 -adrenergic receptor blockers may improve erectile function; however, ejaculatory dysfunction with one of these agents, tamsulosin, occurs at a rate of 4-18%, rising to 30% with long-term use. In addition, treatment with the 5a-reductase inhibitor finasteride is associated with problems of ejaculation (2.1-7.7%), erection (4.9-15.8%), and libido (3.1-5.4%). Such significant and undesirable complications in relation to sexual function produce a welldocumented negative impact on quality of life. Thus, optimal treatment for men with BPH requires the use of agents that demonstrate efficacy and safety with fewer sexual side effects.

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Section: Components Of Quality Of Life In Bphmentioning

confidence: 99%

Section: Components Of Quality Of Life In Bphmentioning

confidence: 99%

Medical therapy for benign prostatic hyperplasia: sexual dysfunction and impact on quality of life

Carbone

Hodges

2003

Int J Impot Res

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“…Participants ranged in age from 27 to 82 years (mean, 57.6). The mean total I-PSS score was 21.9 out of 35 (range 8-34), the mean storage score was 9.3 out of 15 (range [4][5][6][7][8][9][10][11][12][13][14][15] and the mean voiding score was 12.7 out of 20 (range [3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20].…”

Section: Resultsmentioning

confidence: 99%

“…[6][7][8] Elderly women report on micturition symptoms similarly to age-matched men, as recently proved by the use of the American Urological Association Symptom Index (AUASI) or the International Prostate Symptom Score (I-PSS), which was originally designed for the diagnostic workup of men with LUTS. 9 In the case of women with lower urinary tract symptoms, many of the studies are disproportionately weighted toward incontinence. Many women have bothersome lower urinary tract symptoms.…”

Section: Introductionmentioning

confidence: 99%

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Transurethral resection in women with lower urinary tract symptoms

Qiu

Shen

2004

Int J of Urology

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Background : To evaluate the preliminary safety, efficacy and complications of transurethral resection (TUR) in the management of women with lower urinary tract symptoms. Methods : One hundred and eight women (mean age, 57.6 years) with moderate to severe lower urinary tract symptoms underwent TUR between September 1998 and December 2002. At preoperative baseline, 6 months and 24 months postoperatively, all patients underwent clinical evaluations including the standardized American Urological Association symptom score, peak urine flow, postvoid residual urine volume and quality-of-life assessments. Operative time, catheter time, hospital stay and incidence of side-effects were also recorded.Results : The total mean operative time was 19.25 ± 6.70 min. The mean catheter time was 26.2 ± 12.8 h and the mean hospital stay was 2.08 ± 0.84 days. No patient needed a blood transfusion or experienced hyponatremia. The total storage and voiding symptom scores and quality of life score had improved significantly 6 months after the surgical procedure (P < 0.01). There were little changes in peak flow rate and residual urine volume. Complications of the procedure included urinary tract infections (n = 4) and stress incontinence (n = 3). Two patients later underwent bladder neck suspension procedure. Conclusions : In this preliminary study, there was significant clinical improvement maintained at all follow-up intervals and the results were not comparable to TUR of the prosatate in men with clinical benign prostatic hyperplasia. The risks associated with TUR in women, especially of stress incontinence, are significant. A multicenter clinical trial is currently underway to determine the long-term efficacy and safety of TUR in women.

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Effects of finasteride on health-related quality of life in men with symptomatic benign prostatic hyperplasia

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Natural history of prostatism: Impact of urinary symptoms on quality of life in 2115 randomly selected community men

Cited by 130 publications

References 20 publications

Medical therapy for benign prostatic hyperplasia: sexual dysfunction and impact on quality of life

Medical therapy for benign prostatic hyperplasia: sexual dysfunction and impact on quality of life

Transurethral resection in women with lower urinary tract symptoms

Effects of finasteride on health-related quality of life in men with symptomatic benign prostatic hyperplasia

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