Natural history of psychological reaction to genital herpes: a prospective study of woman university students

Hillard, James R.; Hillard, Paula; Kitchell, C.; Birch, Linda; Brennan, Constance; Grubb, Paula L.

doi:10.3109/01674828909016688

Cited by 3 publications

(35 citation statements)

References 18 publications

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“…Among those that scored positively for Q4 (Were objective, standard criteria used for measurement of the condition?) it is important to note that four studies 17,20,49,70 employed previously validated tools in addition to instruments that they had designed themselves, which were lacking in measures of reliability and validity. In relation to whether outcomes were measured in a valid and reliable way (Q7), two studies scored negatively, 68,69 two were unclear, 54,70 and the rest scored positively.…”

Section: Resultsmentioning

confidence: 99%

“…All but two studies reported the participants’ ages 53,54 . The mean age was reported across 21 studies (across 22 publications) 17,20,26,31,48-50,52,53,57-60,62-64,66-68,70,72,73 and ranged from 21.4 to 41.2 years. Two studies reported a median age of 36 years 65 and 35 years 69 .…”

Section: Resultsmentioning

confidence: 99%

“…Twelve studies did not state the length of time since diagnosis 48,50,52,53,56,57,60,61,63,65,68,71 . For those that did, this was either reported as the mean (n = 9 studies, across 10 publications), 17,26,31,51,53,58,66,67,70,73 which ranged from 1.4 to 7.6 years; the median (n = 2) 54,69 of between 5.7 and six years, or the range (n = 8) 14,20,22,49,59,62,64,72 . Three studies 14,49,52 included newly diagnosed patients who were experiencing their primary episode of genital herpes.…”

Section: Resultsmentioning

confidence: 99%

“…Depression was explored across 10 cross-sectional studies 14,17,48,49,52,53,68,70,72,73 . Four used the HADS, 14,48,52,72 two used the BDI, 70,73 and four studies asked single-item questions within generic HRQoL or disease-specific QoL questionnaires 17,49,53,68 .…”

Section: Resultsmentioning

confidence: 99%

“…Any disagreements that arose between the reviewers were resolved through discussion. Five studies compared individuals with genital herpes to other patient groups, including controls from genitourinary or dermatology departments, 48 controls from a stress clinic, 49 or controls with other diseases that included gonorrhea, 50 genital human papillomavirus, or human immunodeficiency virus (HIV), 51 or individuals with other STIs without genital signs and symptoms 52 . For the purposes of this review, only data relating to the individuals with genital herpes were extracted.…”

Section: Methodsmentioning

confidence: 99%

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Impact of primary and recurrent genital herpes on the quality of life of young people and adults: a mixed methods systematic review

Bennett

Rebafka

Carrier

et al. 2022

JBI Evidence Synthesis

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Objective:This review sought to identify the experiences of persons living with genital herpes and what interventions improve the health-related quality of life of young people and adults with primary or recurrent genital herpes.Introduction:Genital herpes is commonly associated with psychosocial challenges. However, a growing body of evidence suggests that its impact can be ameliorated through pharmacological and psychosocial interventions.Inclusion criteria:This review considered English- and German-language studies of community-dwelling males and females, of any ethnicity and geographical location, aged 15 years and older, who had primary or recurrent genital herpes. The quantitative component of the review included studies that reported on the virus’ impact on patients’ health-related quality of life and/or the efficacy of interventions in improving their health-related quality of life. Studies compared antiviral suppression therapies and psychological interventions with usual care or placebo, or against one another. The qualitative component of the review included studies that investigated the perceptions and experiences of young people and adults with genital herpes.Methods:Eleven databases were searched from January 1980 to March 2020. The JBI approach to mixed methods systematic reviews was followed at each stage of the review, and a convergent segregated approach to synthesis and integration was adopted.Results:A total of 31 publications covering 30 studies were deemed suitable for inclusion. Studies encompassed quantitative (n = 27, across 28 publications), qualitative (n = 1), and mixed methods (n = 2) designs. Critical appraisal scores were variable, particularly among the randomized controlled trials and the analytical cross-sectional studies. All studies were included regardless of methodological quality. The quantitative components identified that depression, illness concern, stress, anxiety, isolation, stigma, and a lowering of self-esteem, self-concept, self-confidence, and health-related quality of life may be experienced by both those newly diagnosed with genital herpes and those with recurrences. It was also identified that genital herpes can have an adverse effect on work or school, sexual relationships, and relationships with friends and family. Depression was found to significantly decrease after self-hypnosis and certain psychosocial interventions. Anxiety significantly decreased following pharmacological treatment, psychosocial interventions, and hypnosis. Psychosocial interventions significantly improved mood, and a self-help module with counseling significantly improved participants’ satisfaction with intimate relationships and their self-esteem. Pharmacological treatment significantly improved health-related quality of life; however, there were no significant differences between different active treatment regimens. The qualitative component of the review led to the identification of two synthesized findings: “Disclosure of a diagnosis of genital herpes poses a dilemma for people...

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Section: Resultsmentioning

confidence: 99%