Natural history of retinopathy of prematurity: A prospective study

Fielder, Alistair R.; Shaw, David E.; Robinson, J; Ng, Y K

doi:10.1038/eye.1992.46

Cited by 145 publications

(83 citation statements)

References 34 publications

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“…While comparison between different racial groups was not possible in our study due to the small number of light coloured fundi, this study supports the findings of other studies [16][17][18] regarding the low occurrence rate of ROP especially of advanced disease in black patients or darkly pigmented fundi.…”

Section: Eyesupporting

confidence: 90%

Retinopathy of prematurity in South Africans at a tertiary hospital: a prospective study

Mayet

Cockinos

2005

Eye

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Background and Objectives World Health Organization's vision 20/20 programme has recognized retinopathy of prematurity (ROP) as an important cause of childhood blindness in industrialized and middle-income countries. While ROP is virtually nonexistent in many African countries, ROP is seen in urban areas where facilities for neonatal care exist. The aim of this study is to establish the frequency of ROP in a cohort of patients screened for ROP and to establish if current screening criteria apply to our patients. Patients and Methods Infants with birth weight (BW) of 1500 g or less and/or gestational age of 32 weeks or less were screened for ROP over a 2 1 2 Àyear period by a single examiner. Results ROP was observed in 84 of 514 (16.3%) of infants included for analysis. Threshold disease (tROP) was noted in 1.6% of the total cohort although 41/84 babies with ROP were lost prior to regression or progression to tROP. Of the 43/84 adequately followed up, eight (18.6%) developed tROP. An estimated frequency of tROP was more likely to be 2.9%. There was no tROP noted in babies of BW greater than 1250 g. Gestational age was an unreliable risk parameter in our population. Conclusion The projected occurrence rate of tROP is similar to that found in black population in the Multicentre Cryotherapy for ROP Trial. Our data suggest that the screening criterion based on BW can safely be lowered to 1250 g in our population.

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Section: Eyesupporting

confidence: 90%

Retinopathy of prematurity in South Africans at a tertiary hospital: a prospective study

Mayet

Cockinos

2005

Eye

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“…6,7 Stage 3 ROP is unusual in babies born at or after 30 weeks gestation. Our unit has screened 2960 infants of whom stage 3 ROP has been found in five other babies with birth weight >1500 g. Their birth weights and GA were as follows: 1502 g, GA 32 weeks; 1560 g, GA 31 weeks; 1600 g, GA 31 weeks; 1600 g, GA 30 weeks; 1800 g, GA 31 weeks.…”

Section: Discussionmentioning

confidence: 99%

An unusual case of retinopathy of prematurity

2007

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“…The receiver operator response curve depicts that the model could discriminate the risk factors in 85.66% of the babies weighing between 1501 and 1800 g correctly in babies weighing ≤1800 g was less as compared to various Western studies [7][8][9][10] and previous studies done in Indian scenario. [10,15] This study found low birth weight and low gestational age to be statistically signifi cant for the causation of ROP; as also has been found by authors of previous studies.…”

Section: Figure 1bmentioning

confidence: 99%

“…Incidence of ROP varies in different neonatal units. [5,7] It has been reported to vary from 21% to 65.8% [7][8][9][10] in western studies and 34.9-60.1%. [10,11] in Indian studies.…”

Section: Introductionmentioning

confidence: 99%

Retinopathy of prematurity in babies weighing <1800 g; with special reference to babies weighing between 1501 and 1800 g: An experience from a tertiary care hospital in Delhi

Kapoor

Talwar

Sachdeva

et al. 2014

Int J Med Public Health

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Background: Retinopathy of prematurity (ROP) is a disease related to low birth weight, prematurity, oxygen administration, and various other factors, which are yet to be identifi ed. Aims: The aim was to fi nd incidence of ROP and risk factors for causation in babies weighing <1800 g; and in the babies weighing between 1501 and 1800 g. Design: Prospective study. Materials and Methods: Neonates weighing ≤1800 g taking birth in our institution from January 2011 to January 2012 for a span of 1 year; were included in the study. The data were analyzed to determine risk factors for ROP causation. Information was collected using the standardized performa which included the maternal risk factors as well. Infants were classifi ed by ophthalmologic examination fi ndings using ICROP revisited. Statistics: Qualitative data were analyzed using Pearson's Chi-square test with Yates correction or Fisher's exact test and possible risk factors were analyzed by univariate analysis and multivariate analysis. Results: A total of 278 subjects was included in the study. Incidence of ROP in babies ≤1800 g was found to be 13.67% (38/278). Incidence of ROP in babies weighing between 1501 and 1800 g was 11.64% (17/146). Twenty-one risk factors were signifi cant on univariate analysis in babies weighing ≤1800 g and 18 risk factors in the babies weighing between 1501 and 1800 g. Multiple gestations (P < 0.01), blood transfusion (P < 0.01), antepartum hemorrhage (P < 0.01), pregnancy-induced hypertension (P < 0.01), mechanical ventilation (MV) (P < 0.01), and APGAR at 1 min (P < 0.01) were found to be independently signifi cant for ROP causation on logistic regression analysis in babies weighing ≤1800 g and MV (P < 0.01) and resuscitation (P < 0.01) were signifi cant for babies weighing 1501-1800 g. Conclusion: It should be considered to incorporate screening of babies ≤1800 g uniformly in developing nations. It is recommended that further studies be done taking representative population of babies in different sites with adequate follow-up.

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Natural history of retinopathy of prematurity: A prospective study

Cited by 145 publications

References 34 publications

Retinopathy of prematurity in South Africans at a tertiary hospital: a prospective study

Retinopathy of prematurity in South Africans at a tertiary hospital: a prospective study

An unusual case of retinopathy of prematurity

Retinopathy of prematurity in babies weighing <1800 g; with special reference to babies weighing between 1501 and 1800 g: An experience from a tertiary care hospital in Delhi

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