Natural hollow clay nanotubes and their applications as polymer nanocomposites in tissue engineering

Wong, Li Wen; Goh, Calvin Bok Sun; Pasbakhsh, Pooria; Tan, Joash Ban Lee

doi:10.1016/j.jsamd.2022.100431

Cited by 10 publications

(3 citation statements)

References 111 publications

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“…The main reason is that HNTs are composed of hydrous aluminosilicate with a native tubular structure that can be easily obtained from natural resources. Along with its biocompatibility with human body, HNTs has been proposed as an interesting, valuable and low-cost alternative for bone tissue engineering applications [ 245 , 247 ]. Huang et al (2019) reported the successful incorporation of HNTs into a GelMA hydrogel by photopolymerization process and that HNTs addition increased the mechanical performance and the capability to support cell adhesion and proliferation of human dental pulp stem cells [ 246 ].…”

Section: Hybrid Hydrogel Compositesmentioning

confidence: 99%

Novel Trends in Hydrogel Development for Biomedical Applications: A Review

et al. 2022

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Nowadays, there are still numerous challenges for well-known biomedical applications, such as tissue engineering (TE), wound healing and controlled drug delivery, which must be faced and solved. Hydrogels have been proposed as excellent candidates for these applications, as they have promising properties for the mentioned applications, including biocompatibility, biodegradability, great absorption capacity and tunable mechanical properties. However, depending on the material or the manufacturing method, the resulting hydrogel may not be up to the specific task for which it is designed, thus there are different approaches proposed to enhance hydrogel performance for the requirements of the application in question. The main purpose of this review article was to summarize the most recent trends of hydrogel technology, going through the most used polymeric materials and the most popular hydrogel synthesis methods in recent years, including different strategies of enhancing hydrogels’ properties, such as cross-linking and the manufacture of composite hydrogels. In addition, the secondary objective of this review was to briefly discuss other novel applications of hydrogels that have been proposed in the past few years which have drawn a lot of attention.

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Section: Hybrid Hydrogel Compositesmentioning

confidence: 99%

Novel Trends in Hydrogel Development for Biomedical Applications: A Review

et al. 2022

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“…9,10 Although looking for new green nanocomposites is the topic of plenty of investigations, only a few among them have been commercialized. 11,12 Thus, investigating new biomaterials, new techniques of processing, and property optimization as well as understanding the effect of each component within a whole bionanocomposite are key toward the progression of green nanocomposites fabrication and utilization. 13 The hydrophilicity of bionanocomposites is the golden key, making them a practical option for biomedical applications such as cell and tissue engineering.…”

Section: Introductionmentioning

confidence: 99%

“…There are different available techniques to fabricate bionanocomposites. To name but a few, we can address electrospinning, melt-extrusion, solution mixing, and in situ polymerization/copolymerization reactions. − Over the past few years, demands for green composites/nanocomposite and their usage in biological systems have accelerated due to the environmental concerns arising from the use of synthetic plastics. , Although looking for new green nanocomposites is the topic of plenty of investigations, only a few among them have been commercialized. , Thus, investigating new biomaterials, new techniques of processing, and property optimization as well as understanding the effect of each component within a whole bionanocomposite are key toward the progression of green nanocomposites fabrication and utilization …”

Section: Introductionmentioning

confidence: 99%

Green Polymer Nanocomposites for Skin Tissue Engineering

Shokrani

Jouyandeh

et al. 2022

ACS Appl. Bio Mater.

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Fabrication of an appropriate skin scaffold needs to meet several standards related to the mechanical and biological properties. Fully natural/green scaffolds with acceptable biodegradability, biocompatibility, and physiological properties quite often suffer from poor mechanical properties. Therefore, for appropriate skin tissue engineering and to mimic the real functions, we need to use synthetic polymers and/or additives as complements to green polymers. Green nanocomposites (either nanoscale natural macromolecules or biopolymers containing nanoparticles) are a class of scaffolds with acceptable biomedical properties window (drug delivery and cardiac, nerve, bone, cartilage as well as skin tissue engineering), enabling one to achieve the required level of skin regeneration and wound healing. In this review, we have collected, summarized, screened, analyzed, and interpreted the properties of green nanocomposites used in skin tissue engineering and wound dressing. We particularly emphasize the mechanical and biological properties that skin cells need to meet when seeded on the scaffold. In this regard, the latest state of the art studies directed at fabrication of skin tissue and bionanocomposites as well as their mechanistic features are discussed, whereas some unspoken complexities and challenges for future developments are highlighted.

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How Environmental Chemicals of Concern Emerge: ILs and HNTs

Nelson

2023

Challenges and Advances in Computational Chemistry and Physics

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Natural hollow clay nanotubes and their applications as polymer nanocomposites in tissue engineering

Cited by 10 publications

References 111 publications

Novel Trends in Hydrogel Development for Biomedical Applications: A Review

Novel Trends in Hydrogel Development for Biomedical Applications: A Review

Green Polymer Nanocomposites for Skin Tissue Engineering

How Environmental Chemicals of Concern Emerge: ILs and HNTs

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