2023
DOI: 10.1101/2023.11.16.567430
|View full text |Cite
Preprint
|
Sign up to set email alerts
|

Natural killer cell cytotoxicity shapes the clonal evolution of B cell leukaemia

Michelle C. Buri,
Mohamed R. Shoeb,
Aleksandr Bykov
et al.

Abstract: The term cancer immunoediting describes the dual role by which the immune system can both suppress and promote tumour growth and is divided into three phases: elimination, equilibrium and escape. While the importance of CD8+T cells in all three phases of cancer immunoediting is well-established, the role of NK cells has mainly been attributed to the elimination phase. Here we show that NK cells play a prominent role in all three phases of cancer immunoediting. Extended co-culturing of DNA barcoded mouse BCR/AB… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

0
0
0

Publication Types

Select...

Relationship

0
0

Authors

Journals

citations
Cited by 0 publications
references
References 110 publications
0
0
0
Order By: Relevance

No citations

Set email alert for when this publication receives citations?