Natural Products and Disease Prevention, Relief and Treatment

Abstract

This Special Issue focusses on the role of natural products in disease prevention, relief and treatment [...]

Therapeutic, and pharmacological prospects of nutmeg seed: A comprehensive review for novel drug potential insights

“…Natural products, and functional foods offer natural remedies that have been used to treat many illnesses ( Zhu et al, 2022 , Kim et al, 2018 ). They play a significant role in regulating fundamental pathophysiological reactions such as oxidative damage, inflammatory processes, fibrosis, and hypoxia ( Islam, 2022 ). Nutmeg seed poses a remarkable chemical composition that can prevent heart disease, diabetes, hyperlipidemia, and reduce lipid oxidation ( Pratiwi et al, 2018 , Parvin et al, 2023 ).…”

Targeting Neutrophil Extracellular Traps in Gouty Arthritis: Insights into Pathogenesis and Therapeutic Potential

“…The enduring utilization of natural products underscores their enduring relevance and ongoing impact in addressing a diverse array of health conditions, highlighting their continued importance as an invaluable asset in the realm of modern healthcare practices. 257 Resveratrol is a natural polyphenolic compound found in a variety of plant species, including grapes, peanuts, and berries. It contains numerous potential health benefits, including anti-inflammatory, antioxidant, and anti-aging properties.…”

“…In addition, natural products may possess a multiplicity of targets, which can lead to low bioavailability, poor pharmacokinetics, or toxic effects. 257,301 On the other hand, synthetic products exhibit drawbacks including but not limited to high expense, instability, and potential immunogenicity. Synthetic compounds may also lack specificity and biological relevance toward NET-targeted inhibition.…”

Natural products modulate cell apoptosis: a promising way for treating endometrial cancer

“…NPs possess anti-cancer, anti-inflammatory, antioxidant, anti-bacterial, analgesic, anti-diabetic, and enzyme-inhibitory activities ( Hassan et al, 2022 ). In recent years, the anti-cancer effects of NPs have drawn increasing attention ( Hassan et al, 2022 ; Islam, 2022 ; Nuzzo et al, 2022 ), and we focus on their apoptosis-regulatory effect. Existing studies suggest that NPs can promote EC cell apoptosis through multiple pathways and thus exert anti-EC effects.…”