Infections of cultivated plants, transmitted by fusariosis agents, are among the most harmful factors for humans in grain production. Thus, there is an obvious need for effective control over harmfulness of fusariosis agents in agrophytocenoses. Summarizing scienti¿ c data on the issues of forming the strategy of decreasing harmfulness of fusariosis agents in agrocenoses. The major factors of decreasing the level of infecting cereal crops with fusarioses are genetic improvement of plants via selection of species and hybrids, resistant to infections, agrotechnical means and chemical control using modern fungicides with a high level of inhibiting the development of the agent during the whole growing season. The main attention should be paid to controlling the presence and prevalence of infections of plants by such species