Natural Super-Disintegrant Agents Used in Various Oral Solid Dosage Forms

Abstract

Super-disintegrating agents are one of the ingredients used in pharmaceutical solid dosage forms. These substances play a vital role in formulation design. Natural super-disintegrants have gained more popularity due to their oral bioavailability. It disintegrates the tablets into smaller particles to enhance the dissolution rate. Fast dissolving, chewable tablets, and other orally administered dosage forms consist of super-disintegrating agents which shows rapid and quick action. Natural super disintegrating agents in pharmaceutical dosage forms are very effective due to their ecofriendly nature as well as these are biocompatible and biodegradable. These are abundantly and cheaply available from nature.Today the researchers are focusing on naturally available excipients.
 Keywords: Natural Superdisintegrants, Disintegration, Bioavailability, Biocompatible, Biodegradable.

Garden cress seeds: a review on nutritional composition, therapeutic potential, and industrial utilization

“…Garden cress seeds contains mucilage, which functions primarily based on swelling mechanisms that act as binders and disintegrating agents. Compared to leaves, seeds often have a higher mucilage concentration (Iswariya et al., 2021 ). In fact, research comparing natural and synthetic superdisintegrants found that L. sativum mucilage performed better overall than the synthetic alternative (Dixit Jr et al., 2020 ).…”