Naturally-Occurring Dibenzofurans. VIII. The Synthesis of Isodidymic Acid

Abstract

The synthesis of the lichen dibenzofuran isodidymic acid (2)(3-hydroxy- 7-methoxy-9-pentyl-1-propyldibenzofuran-2-carboxylic acid) by intramolecular Ullmann coupling of methyl 3-iodo-4-(2′-iodo-5′-methoxy- 3′-pentylphenoxy)-6-methoxy-2-propylbenzoate (22), and further transformations, is described.