Nature of a white opaque substance visualized by magnifying endoscopy in colorectal hyperplastic polyps

Hirano, Akikazu; Yao, Kenshi; Ishiguro, Hiroshi; Hisabe, Takashi; Imamura, Kentaro; Kanemitsu, Takao; Ohtsu, Kensei; Hasegawa, Rino; Ikezono, Go; Takeda, Kazuhiro; Miyaoka, Masaki; Ueki, Toshiharu; Tanabe, Hiroshi; Haraoka, Seiji; Iwashita, Akinori

doi:10.1055/a-1452-9669

Cited by 4 publications

(2 citation statements)

References 14 publications

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“…Additionally, white opaque substance (WOS) is a well-known whitish change of colonic mucosa detected in adenoma, SSL, and HP and it was positive for the immunohistochemical stain of adipophilin. 32,33 WDC was considered to be related with WOS because stain of adipophilin was seen in WDC area. However, WDC area and positive of adipophilin was not consistent perfectly.…”

Section: Discussionmentioning

confidence: 99%

The comparison of diagnostic ability between blue laser/light imaging and narrow band imaging for sessile serrated lesions with or without dysplasia

Kobayashi,

Yoshida,

Morinaga

et al. 2023

Preprint

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Objectives: Diagnostic ability of sessile serrated lesions (SSL) and SSL with dysplasia (SSLD) using blue laser/light imaging (BLI) has not been well examined. We analyzed the diagnostic accuracy of BLI for SSL and SSLD using several endoscopic findings compared to those of narrow band imaging (NBI). Materials and Methods: This was a subgroup analysis of prospective studies. 476 suspiciously serrated lesions of ≥2 mm on the proximal colon showing serrated change with magnified NBI or BLI in our institution between 2014 and 2021 were examined histopathologically. After propensity score matching, we evaluated the diagnostic ability of SSL and SSLD of the NBI and BLI groups regarding various endoscopic findings. For WLI findings, granule, depression, reddish were examined for diagnosing SSLD. For NBI/BLI findings, expanded crypt opening (ECO) or thick and branched vessels (TBV) were examined for diagnosing SSL. Network vessels (NV) and white dendritic change (WDC) defined originally were examined for diagnosing SSLD. Results: Among matched 176 lesions, the sensitivity of lesions with either ECO or TBV for SSL in the NBI/BLI group were 97.5%/98.5% (p=0.668). Those with either WDC or NV for diagnosing SSLD in the groups were 81.0%/88.9% (p=0.667). Regarding the rates of endoscopic findings among 30 SSLD and 290 SSL, there were significant differences in WDC (66.4% vs. 8.6%, p<0.001), NV (55.3% vs. 1.4%, p<0.001), and either WDC or NV (86.8% vs. 9.0%, p<0.001). Conclusions: The diagnostic ability of BLI for SSL and SSLD was not different from NBI. NV and WDC were useful for diagnosing SSLD.

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Section: Discussionmentioning

confidence: 99%

The comparison of diagnostic ability between blue laser/light imaging and narrow band imaging for sessile serrated lesions with or without dysplasia

Kobayashi,

Yoshida,

Morinaga

et al. 2023

Preprint

View full text Add to dashboard Cite

show abstract

“… 16 The caps are also soft and round, which minimizes damage to the friable mucosa. 17 Attaching a cap helps endoscopes stay on focus throughout the exam, allowing endoscopists to quickly and easily obtain images of desired lesions that are on focus.…”

Section: Provision Of a Constant Distance From A Lesion For Clear Vis...mentioning

confidence: 99%

The role of cap-assisted endoscopy and its future implications

Kim,

Lee

2024

Clin Endosc

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Cap-assisted endoscopy refers to a procedure in which a short tube made of a polymer (mostly transparent) is attached to the distal tip of the endoscope to enhance its diagnostic and therapeutic capabilities. It is reported to be particularly useful in: (1) minimizing blind spots during screening colonoscopy, (2) providing a constant distance from a lesion for clear visualization during magnifying endoscopy, (3) accurately assessing the size of various gastrointestinal lesions, (4) preventing mucosal injury during foreign body removal, (5) securing adequate workspace in the submucosal space during endoscopic submucosal dissection or third space endoscopy, (6) providing an optimal approach angle to a target, and (7) suctioning mucosal and submucosal tissue with negative pressure for resection or approximation. Here, we review various applications of attachable caps in diagnostic and therapeutic endoscopy and their future implications.

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Multispectral endoscopic imaging studies on the tissue components of gastrointestinal mucosa

Yuan²,

Wang³

2022

Advanced Optical Imaging Technologies V

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In recent years, endoscopic imaging has become the major diagnostic approach for early cancer. It is difficult to accurately obtain the information of lesions and components content by using conventional white light imaging (C-WLI). Multispectral imaging techniques such as narrowband imaging are widely used in endoscopic clinical because of their specificity on the surface structure of digestive tract mucosa. However, there is still a lack of multispectral techniques for tissue components specificity. Tissue components such as lipid, hemoglobin are closely related to the generation and development of tumors, but it is difficult to observe the characteristics of lipid and hemoglobin by conventional white light imaging. Therefore, we studied the multispectral endoscopic imaging technique for the analysis of digestive tract mucosal components. Based on the reflectance spectrum characteristics of these tissue components, we determined their specific wavelength, and comprehensively considered the absorption, scattering, oxygenation and others in order to determine the most appropriate optical band in the wavelength range of 365-660nm. Through experimental verification, we choose different narrow-band wavelength combinations for lipids and hemoglobin oxygen saturation respectively to achieve multispectral imaging. In order to simulate the optical properties of digestive tract surface, we made tissue optical phantom. At the same time, we tested and optimized the imaging system and algorithm by the experiments in vitro, and obtained the optimal multispectral image of tissue components, then realize the quantitative detection combined with the content analysis algorithm. Our pilots show that the multispectral imaging system can improve the contrast of endoscopy image, enhance the detail information, achieve high precision detection of tissue components content, and control the error within 10%.

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Nature of a white opaque substance visualized by magnifying endoscopy in colorectal hyperplastic polyps

Cited by 4 publications

References 14 publications

The comparison of diagnostic ability between blue laser/light imaging and narrow band imaging for sessile serrated lesions with or without dysplasia

The comparison of diagnostic ability between blue laser/light imaging and narrow band imaging for sessile serrated lesions with or without dysplasia

The role of cap-assisted endoscopy and its future implications

Multispectral endoscopic imaging studies on the tissue components of gastrointestinal mucosa

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