Nature of "basal" and "reserve" cells in oviductal and cervical epithelium in man.

Abstract

SUMMARY The epithelium of the human fallopian tube (oviduct) and cervix were studied by histological, immunohistological, and ultrastructural methods with a view to establishing the nature of the so called "basal" and "reserve" cells. The results indicated that the "basal" cells of the oviductal epithelia were T lymphocytes, with a predominance of T cytotoxic and suppressor cells. A more heterogeneous inflammatory cell population was present in cervical epithelium, although once again T cytotoxic and suppressor cells were the most numerous subtype. The intraepithelial inflammatory cells were quite distinct from the cells commonly referred to as "reserve" cells (reserve cell hyperplasia), which have epithelial characteristics.

The Sow Endosalpinx at Different Stages of the Oestrous Cycle and at Anoestrus: Studies on Morphological Changes and Infiltration by Cells of the Immune System

“…Lymphocyte subpopulations in the oviductal mucosa have been described in humans (Morris et al 1986;Peters 1986;. However, to our knowledge, the present study is one of the first to describe leukocyte subpopulations in the pig oviduct.…”

“…For toluidine blue stained sections, the immune cells with typically small to medium sized, round to oval and densely stained nuclei surrounded by a thin rim of cytoplasm as described by Peters (1986) were counted as lymphocytes. Cells with phagosome-like bodies in the cytoplasm were counted as macrophages.…”

Expression of Sox2 in human cervical carcinogenesis

“…Sox2 staining in normal cervical epithelium was found only in the basal cells, where epithelial "reserve" cells were located. Whether these Sox2 positive cells are stem cells in normal cervical epithelia, which was thought by Peters [26] and Smedts [27] more than 20 years ago, or these positive cells are initiating cells for precancerous lesions requires further study.…”

Stem‐Like Epithelial Cells Are Concentrated in the Distal End of the Fallopian Tube: A Site for Injury and Serous Cancer Initiation

“…The literature uses the terms peg and intercalary interchangeably; therefore, we will refer to this distinct cell type in the fallopian tube epithelium as the peg cell. Another cell type called the ''basal'' or ''reserve'' cell has been previously observed in the fallopian tube [16]. These cells with a clear cytoplasmic halo were found to be lymphoid based on the expression of leukocyte common antigen and the absence of epithelial markers [16,17].…”