1976
DOI: 10.1111/j.1476-5381.1976.tb07469.x
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Nature of Histamine Receptors in the Emetic Chemoreceptor Trigger Zone

Abstract: I The protective effects of the intracerebroventricular (i.c.v.)

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Cited by 44 publications
(9 citation statements)
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“…We believe that morphine induces emesis by an action on the enkephalin receptors in the emetic trigger zone and apomorphine may be acting on dopamine receptors in the CTZ. There is already evidence in support of histamine receptors in the chemoreceptor trigger zone (Bhargava & Dixit, 1968;Bhargava, Dixit & Palit, 1976). Thus, there may be a variety of receptors in the CTZ.…”
Section: Discussionmentioning
confidence: 99%
“…We believe that morphine induces emesis by an action on the enkephalin receptors in the emetic trigger zone and apomorphine may be acting on dopamine receptors in the CTZ. There is already evidence in support of histamine receptors in the chemoreceptor trigger zone (Bhargava & Dixit, 1968;Bhargava, Dixit & Palit, 1976). Thus, there may be a variety of receptors in the CTZ.…”
Section: Discussionmentioning
confidence: 99%
“…The area postrema is important as a relay in mammalian brain for taste aversion and vomiting reflexes, through µ opioid, 5HT3 and H2 receptor binding (Bhargava et al. 1976; Gutstein & Akil 2001; Japundzic‐Zigon et al.…”
Section: Introductionmentioning
confidence: 99%
“…11 The area postrema is important as a relay in mammalian brain for taste aversion and vomiting reflexes through μ-opioid, 5HT3, and H2 receptor binding. 2,8,9 Moreover, many peptides, such as angiotensin, adrenomedullin, endothelin, and endorphin, regulate cardiovascular functions 1,12,14 by binding on receptors located in the area postrema, the regulatory function of which is mediated through efferent projections toward other medullary centers. 6,7,15 It is not clear what impact the Chiari I malformation had on the present case.…”
Section: Discussionmentioning
confidence: 99%