Nausea and vomiting in palliative care

Leach, Charlotte

doi:10.7861/clinmedicine.19-4-299

Cited by 21 publications

(14 citation statements)

References 12 publications

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“…The results of this study also showed that the likelihood of developing psychosocial distress was higher among cancer patients with severe nausea when compared to patients with no severe nausea. This result was consistent with ndings from other studies (79). This could be due to the fact that nausea is still a serious side effect of cancer therapy, frequently resulting in dramatic changes in the patient's emotions, social activities, and work situations.…”

Section: Discussionsupporting

confidence: 92%

Psychosocial distress and associated factors among adult cancer patients at oncology units in the Amhara regional state, Ethiopia, 2022

Baye

Bogale

Tegenaw

et al. 2022

Preprint

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Background Psychosocial distress is a long-term burden for cancer survivors, which has an impact on their quality of life and oncologic prognosis. Although the national cancer prevention and control program in Ethiopia has made efforts in cancer prevention, control, and management by implementing the national cancer control plan 2016–2020, no enough evidence about psychosocial distress among adult cancer patients. So it is critical to understand the magnitude of psychosocial distress and the factors that contribute to it. Objective To assess the prevalence of psychosocial distress and associated factors among adult cancer patients at oncology units in the Amhara regional state, Ethiopia. 2022. Methods A multi-center institutional based cross-sectional study was conducted among a sample of 605 adult cancer patients from April 30-June 22, 2022. A systematic random sampling technique was employed to select the study units. And data were collected through interviewers administered questionnaires by using the validated and pretested tools. Distress was assessed using the Questionnaire on Stress in Cancer Patients Revised 10. Both bivariable and multivariable logistic regression was used to describe the association between dependent and independent variables. Independent variable with p-value less than 0.25 in the bivariable logistic regression analyses were entered into multivariable logistic regression model. Variables with p-value < 0.05 in the multivariable logistic regression analyses were considered as statistically significant associated factors of psychosocial distress. Result A total of 593 adult cancer patients took part in this study with mean age of 46.86 ± 14.5 years. The overall prevalence of psychosocial distress was 63.74%. Variables such as being female (AOR = 1.98, 95% CI: 1.24–3.17), patients who lives in rural areas (AOR = 2.3, 95% CI: 1.49–3.54), community based health insurance utilization (AOR = 0.34, 95% CI: 0.23–0.51), patients on chemotherapy treatment (AOR = 2.72, 95% CI: 1.38–5.39), patients with comorbidity (AOR = 3.2, 95% CI: 1.67–6.10), and symptom burdens such as severe fatigue (AOR = 1.65, 95% CI:1.09–2.39) and severe nausea (AOR = 2.07, 95%CI: 1.43-3.00) were statistically associated with psychosocial distress. Conclusion and recommendation: In general, the findings of this study showed a relatively high magnitude in which around two-thirds of patients experienced psychosocial distress. It is better to establish and enforce the integration and coordination of psychosocial-oncology service programs at national level with parallel guidelines and policies.

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Section: Discussionsupporting

confidence: 92%

Psychosocial distress and associated factors among adult cancer patients at oncology units in the Amhara regional state, Ethiopia, 2022

Baye

Bogale

Tegenaw

et al. 2022

Preprint

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“…There were also significant variations in their use across different services depending on their jurisdiction. Antiemetics followed by opioids and benzodiazepines were found to be the highest prescribed AM (Leach, 2019). This is somewhat different from other studies where opioids were considered the main AM prescribed for end-of-life care (Khalil et al, 2019) but consistent with other studies by Bowers et al (2019) where midazolam and opioids were cited as the most prescribed drugs.…”

Section: Main Findingssupporting

confidence: 48%

Mapping end-of-life and anticipatory medications in palliative care patients using a longitudinal general practice database

Khalil

Garett²,

Byrne³

et al. 2021

Pall Supp Care

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Objective End-of-life and anticipatory medications (AMs) have been widely used in various health care settings for people approaching end-of-life. Lack of access to medications at times of need may result in unnecessary hospital admissions and increased patient and family distress in managing palliative care at home. The study aimed to map the use of end-of-life and AM in a cohort of palliative care patients through the use of the Population Level Analysis and Reporting Data Space and to discuss the results through stakeholder consultation of the relevant organizations. Methods A retrospective observational cohort study of 799 palliative care patients in 25 Australian general practice health records with a palliative care referral was undertaken over a period of 10 years. This was followed by stakeholders’ consultation with palliative care nurse practitioners and general practitioners who have palliative care patients. Results End-of-life and AM prescribing have been increasing over the recent years. Only a small percentage (13.5%) of palliative care patients received medications through general practice. Stakeholders’ consultation on AM prescribing showed that there is confusion about identifying patients needing medications for end-of-life and mixed knowledge about palliative care referral pathways. Significance of results Improved knowledge and information around referral pathways enabling access to palliative care services for general practice patients and their caregivers are needed. Similarly, the increased utility of screening tools to identify patients with palliative care needs may be useful for health care practitioners to ensure timely care is provided.

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“…The collection of side effects commonly observed while using VR has been labelled “cybersickness” and is generally reported to consist of symptoms including nausea, dizziness, disorientation, light-headedness, and headaches [ 19 , 20 ]. The prevalence of nausea in palliative care cancer patients has been reported as high as 68% [ 21 ]. Therefore, greater care must be taken when using VR with palliative care patients so as not to exacerbate any existing symptoms.…”

Section: Introductionmentioning

confidence: 99%

Virtual Reality in Palliative Care: A Systematic Review

et al. 2022

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Background: Virtual reality (VR) using head-mounted displays (HMDs) has demonstrated to be an effective tool for treating various somatic and psychological symptoms. Technological advances and increased affordability of VR technology provide an interesting option for delivering psychological interventions to patients in palliative care. The primary aim of this systematic review was to synthesise the available research on the use of VR for enhancing psychological and somatic outcomes for palliative care patients. Secondary aims included assessing general satisfaction and overall usability. Method: A pre-registered systematic literature search was conducted according to PRISMA guidelines using OVID Emcare, Cochrane Library, Embase, Medline, PsycINFO, and PubMed Care Search: Palliative Care Knowledge Network. Peer-reviewed experimental, quasi-experimental, observational, case, and feasibility studies consisting of single or multiple VR sessions using HMDs that reported psychological and/or somatic outcomes were included. Results: Eight studies published between 2019 and 2021 were included, representing 138 patients. While the reported quantitative psychological and somatic outcomes were ambiguous, the qualitative outcomes were largely positive. Participants were generally satisfied with VR, and most studies reported the VR interventions as usable, feasible, and acceptable. Conclusions: VR shows promise in palliative care and generally addresses a range of symptoms with few adverse effects. Future research should consist of adequately powered RCTs evaluating dosage and focusing on providing meaningful activities to enhance outcomes further.

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Nausea and vomiting in palliative care

Cited by 21 publications

References 12 publications

Psychosocial distress and associated factors among adult cancer patients at oncology units in the Amhara regional state, Ethiopia, 2022

Psychosocial distress and associated factors among adult cancer patients at oncology units in the Amhara regional state, Ethiopia, 2022

Mapping end-of-life and anticipatory medications in palliative care patients using a longitudinal general practice database

Virtual Reality in Palliative Care: A Systematic Review

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