Climate change and wildfire effects have continued to receive great attention in recent times due to the impact they render on the environment and most especially to the field of agriculture. The purpose of this study was to assess the synergistic impacts of climate change and wildfires on agricultural sustainability. This study adopted a cross-sectional survey design based on the quantitative research approach. Data were collected from 340 environmental experts using an online questionnaire. The results showed that extreme weather events such as heavy rains or extreme droughts negatively influence agricultural sustainability in Europe. The results showed that disruptions in ecosystems caused by climate change have a significant positive impact on agricultural sustainability in Europe. Furthermore, forest regeneration after wildfires showed statistically significant positive influence on agricultural sustainability in Europe. The economic impact of fire on crops, cattle, and farms can be estimated. This information can be used to develop and plan agricultural regions near fire-prone areas; choose the best, most cost-effective, and longest-lasting cultivar; and limit fire risk. It is also clear that increased wildfire smoke negatively affects agricultural sustainability.