Water levels in the Laurentian Great Lakes have fluctuated dramatically over recent decades. Since 2015, each of the lakes has reached a record high, often following a recent record or near-record low. These exceptional swings have motivated examinations of changes in lake level variability, particularly given the known climate change-driven intensification of the hydrologic cycle. Recent studies have presented evidence of rising lake level variability and changing water balance components (i.e., overlake precipitation, overlake evaporation, and basin runoff), however a full characterization of trends in variability is needed. Here, we build on previous analyses by quantitatively answering the question: are trends in hydrologic interannual variability over the Great Lakes over recent decades -both lake levels and individual hydrologic components -statistically robust, or simply the result of random chance? Using two non-parametric trend tests, we find that interannual variability of lake levels is significantly increasing in Lakes Superior, Michigan-Huron, and Erie, while decreasing in well-regulated Lake Ontario. We also find robust increasing variability in overlake precipitation, overlake evaporation, and basin runoff for the vast majority of lakes. These results suggest that critical work must follow to both attribute causes of detected trends and to determine if trends will continue increasing in the future with continued anthropogenic climate change.