NBT-II cell locomotion is modulated by restricting the size of focal contacts and is improved through EGF and ROCK signaling

Liu, Hong Wen; Lin, Chia Ping; Liou, Yi Jia; Hsu, Kuo Wei; Yang, Jung Yen; Lin, Chi

doi:10.1016/j.biocel.2014.04.009

Cited by 1 publication

(1 citation statement)

References 34 publications

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“…Sometimes, cross-linking can improve cell activity on a gel [36]. In addition, mechanosensing can be an initiator of cell displacement on surfaces (mechanotaxis, discovered by Lo et al [37]), from the soft to the stiff [38] and motility were shown to be linked to focal contacts and thus indirectly to cellular adhesion [39,40].…”

Section: Surfaces and Bioadhesionmentioning

confidence: 99%

PNIPAM grafted surfaces through ATRP and RAFT polymerization: Chemistry and bioadhesion

Conzatti

Cavalié

Combes

et al. 2017

Colloids and Surfaces B: Biointerfaces

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a b s t r a c tBiomaterials surface design is critical for the control of materials and biological system interactions. Being regulated by a layer of molecular dimensions, bioadhesion could be effectively tailored by polymer surface grafting. Basically, this surface modification can be controlled by radical polymerization, which is a useful tool for this purpose. The aim of this review is to provide a comprehensive overview of the role of surface characteristics on bioadhesion properties. We place a particular focus on biomaterials functionalized with a brush surface, on presentation of grafting techniques for "grafting to" and "grafting from" strategies and on brush characterization methods. Since atom transfer radical polymerization (ATRP) and reversible addition-fragmentation chain transfer (RAFT) polymerization are the most frequently used grafting techniques, their main characteristics will be explained. Through the example of poly(N-isopropylacrylamide) (PNIPAM) which is a widely used polymer allowing tuneable cell adhesion, smart surfaces involving PNIPAM will be presented with their main modern applications.

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