Nd:YAG Laser Ophthalmic Microsurgery

In ophthalmology, the use of femtosecond lasers is receiving more attention than ever due to its extremely high intensity and ultra short pulse duration. It opens the highly beneficial possibilities for minimized side effects during surgery process, and one of the specific areas is laser surgery in glaucoma treatment. However, the sophisticated femtosecond laser-ocular tissue interaction mechanism hampers the clinical application of femtosecond laser to treat glaucoma. The potential contribution in this work lies in the fact, that this is the first time a modified moving breakdown theory is applied, which is appropriate for femtosecond time scale, to analyze femtosecond laser-ocular tissue interaction mechanism. Based on this theory, energy deposition and corresponding thermal increase are studied by both simulation and experimentation. A simulation model was developed using Matlab software, and the simulation result was validated through in-vitro laser-tissue interaction experiment using pig iris. By comparing the theoretical and experimental results, it is shown that femtosecond laser can obtain determined ocular tissue removal, and the thermal damage is evidently reduced. This result provides a promising potential for femtosecond laser in glaucoma treatment.

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“…According to the literatures, there are four main models proposed as an attempt to explain laser-induced optical breakdown [6].…”

Section: Therictal Studymentioning

confidence: 99%

“…An ionization process during laser-material process is defined as Laserinduced breakdown (optical breakdown) [6]. Sufficient energy is required to deposit into the material to achieve optical breakdown.…”

Section: Therictal Studymentioning

confidence: 99%

<title>Femtosecond laser for glaucoma treatment: the comparison between simulation and experimentation results on ocular tissue removal</title>

et al. 2005

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“…In this model, it is assumed that electrons are spread out from the plasma volume to create precursors for plasma formation farther away from the focal plane. This assumption does not find great support in the case of liquids [73].…”

Section: Classical Moving Breakdown Modelmentioning

confidence: 90%

“…They are the model of laser-supported detonation waves; the model of traveling ionization waves; the model of radiation transport waves; the moving breakdown model. [73] The laser-supported detonation model was first proposed by Ramsden and Savic [75].…”

Section: Classical Moving Breakdown Modelmentioning

confidence: 99%

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A study of femtosecond laser in glaucoma treatment : energy deposition and thermal increase

Hou¹

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The generation of femtosecond pulsed laser offers completely new possibilities for multiple technical applications. Due to its non-contact processing, extremely high intensity and ultra short pulse duration, it provides precise control of material removal with negligible thermal damage. In ophthalmology, the use of femtosecond lasers is receiving more attention than ever. It opens the highly beneficial possibilities for minimized side effects during the surgery process, and one of the specific areas is laser surgery in glaucoma treatment. Much work has been done for femtosecond laser application in ophthalmology. Some prospective results have been achieved. Meanwhile, the sophisticated interaction mechanism hampers femtosecond lasers' clinical application, and its potential in glaucoma treatment is still at the early stage. In this research, it was the first time that a modified moving breakdown theory was applied to study laser-induced optical breakdown in ocular tissue. It aimed to apply femtosecond laser in iridotomy surgery. Based on this theory, optical breakdown and the corresponding thermal increase were studied. The femtosecond laserinduced moving breakdown model was introduced to simulate the optical breakdown threshold; the Heat Affected Zone model was used to analyze temperature increases in water and ocular tissues. Cyclophotocoagulation is another main method to treat glaucoma. To improve the efficiency of cyclophotocoagulation procedure, a Monte Carlo program was developed and light propagation in multilayered ocular tissue was studied. The i

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Nd:YAG Laser Ophthalmic Microsurgery

Cited by 2 publications

References 47 publications

<title>Femtosecond laser for glaucoma treatment: the comparison between simulation and experimentation results on ocular tissue removal</title>

<title>Femtosecond laser for glaucoma treatment: the comparison between simulation and experimentation results on ocular tissue removal</title>

A study of femtosecond laser in glaucoma treatment : energy deposition and thermal increase

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