Nd-Yag laser treatment of bladder tumours

Kardos, R; Magasi, P; Karsza, A

doi:10.1007/bf02768215

Cited by 13 publications

(2 citation statements)

References 3 publications

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“…These tumours are treated frequently by a combination of surgery, immunotherapy, chemotherapy or radiation therapy . The specific therapeutic protocol following internationally validated clinical guides is selected essentially according to pathological features, such as grade and stage, analysed in the clinical context .…”

Section: Introductionmentioning

confidence: 99%

Iatrogenic changes in the urinary tract

et al. 2016

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A handful of therapeutic procedures are used to treat malignancies of the urinary tract, most frequently intravesical immunotherapy or chemotherapy, but also neoadjuvant systemic chemotherapy. These treatment modalities produce morphological changes in the urothelium that can be mistaken for carcinoma; in particular, these therapies frequently mimic urothelial carcinoma in situ (CIS) urothelial dysplasia or true invasive neoplasia. Drugs such as mitomycin C used after transurethral resection of bladder tumour to reduce recurrences, bacillus Calmette-Guérin (BCG) intravesical immunotherapy to treat high-risk non-muscle-invasive bladder cancer and urothelial CIS and platin-based systemic chemotherapy to improve postcystectomy disease-specific survival are examples of therapy-related atypia seen in the urinary tract. To complicate the pathologist's life, a number of systemic drugs in use to treat other diseases, such cyclophosphamide, used to treat some autoimmune disorders or certain haematological malignancies or, in the case of anaesthetics, ketamine, used increasingly as an illegal recreational drug, may produce similarly relevant atypical changes in the urothelium, and therefore need to be differentiated from intraepithelial neoplasia. Other less frequent procedures, such as photodynamic and laser therapy or the newer gene therapy to treat urothelial neoplasia, remain experimental. An immunohistochemical approach to reactive urothelium versus carcinoma in situ using p53, cytokeratin 20 and CD44 is also valid in the post-therapy setting. The pathologist should be aware of these novelties, as he or she plays a crucial role in evaluating treatment efficacy, but at the same time needs to avoid misdiagnosing secondary atypia as intraepithelial neoplasia.

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Section: Introductionmentioning

confidence: 99%

Iatrogenic changes in the urinary tract

et al. 2016

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“…During the 1980s and 1990s, bladder cancer was treated by Nd:YAG lasers with high power and short time pulses [31,33,34,44]. The main risk is the perforation of the bowel or bladder [45], in particular at high laser power (>50 W) [46], although this has also been reported at 35 W [32].…”

Section: Lasers In Surgerymentioning

confidence: 99%

Laser Ablation for Cancer: Past, Present and Future

Schena

Saccomandi

Fong

2017

JFB

144

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Laser ablation (LA) is gaining acceptance for the treatment of tumors as an alternative to surgical resection. This paper reviews the use of lasers for ablative and surgical applications. Also reviewed are solutions aimed at improving LA outcomes: hyperthermal treatment planning tools and thermometric techniques during LA, used to guide the surgeon in the choice and adjustment of the optimal laser settings, and the potential use of nanoparticles to allow biologic selectivity of ablative treatments. Promising technical solutions and a better knowledge of laser-tissue interaction should allow LA to be used in a safe and effective manner as a cancer treatment.

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Lasers for Bladder Tumors

Smith¹,

Thomas²

2010

New Technologies in Urology

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Nd-Yag laser treatment of bladder tumours

Cited by 13 publications

References 3 publications

Iatrogenic changes in the urinary tract

Iatrogenic changes in the urinary tract

Laser Ablation for Cancer: Past, Present and Future

Lasers for Bladder Tumors

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