2012
DOI: 10.1128/aac.00150-12
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NDM-1-Producing Klebsiella pneumoniae Now in Turkey

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Cited by 49 publications
(39 citation statements)
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“…Considering that previous reports have indicated the international transfer of NDM producers from Iraq to Turkey 27 and France, 28 our findings demonstrate that this region, including Iran, Iraq, and other countries in the Middle East, might be the third reservoir for NDM producers after the Indian subcontinent and Balkan countries. The occurrence of bla NDM-1 in different PFGE types in this study implied an important role for the horizontal spread of NDM in Iran.…”
Section: Discussionmentioning
confidence: 82%
“…Considering that previous reports have indicated the international transfer of NDM producers from Iraq to Turkey 27 and France, 28 our findings demonstrate that this region, including Iran, Iraq, and other countries in the Middle East, might be the third reservoir for NDM producers after the Indian subcontinent and Balkan countries. The occurrence of bla NDM-1 in different PFGE types in this study implied an important role for the horizontal spread of NDM in Iran.…”
Section: Discussionmentioning
confidence: 82%
“…However, these antibiotics frequently show unfavourable pharmacokinetics and adverse effects, mainly in patients with underlying conditions. NDM-1-producing Enterobacteriaceae, in particular K. pneumoniae and Enterobacter cloacae, have been previously reported in Istanbul, Turkey (Poirel et al, 2012(Poirel et al, , 2014. NDM-1-producing K. pneumoniae was probably imported into Turkey from Iraq (Poirel et al, 2012).…”
Section: Discussionmentioning
confidence: 90%
“…NDM-1-producing Enterobacteriaceae, in particular K. pneumoniae and Enterobacter cloacae, have been previously reported in Istanbul, Turkey (Poirel et al, 2012(Poirel et al, , 2014. NDM-1-producing K. pneumoniae was probably imported into Turkey from Iraq (Poirel et al, 2012). NDM-1 has also recently been reported in a strain of Acinetobacter pittii isolated in 2006 in Ankara (Ignasi et al, 2014).…”
Section: Discussionmentioning
confidence: 91%
“…Despite promising in vitro data with colistin, a number of case reports describe clinical failures with colistinbased regimens, or treatment was complicated by the onset of renal impairment (14)(15)(16). This highlights the need for exploration of additional treatment options for managing infections caused by NDM-1-producing organisms.…”
mentioning
confidence: 99%