This work has been carried out to obtain and inspect of At 211 radionuclide through fusion reaction. Cross-sections for fusion reaction have been calculated with different interaction combinations and excitations for F 19 + Os 192 and O 18 + Ir 193 reactions. All calculations have been performed on NRV Knowledge Base, CCFULL code, and Wong's Formula. Firstly, we assigned reaction parameter values taking into account the compatibility with the experimental data F 19 + Os 192 reaction. Afterward, to enrich studies on At 211 radionuclide, we proposed O 18 +Ir 193 reaction which did not have experimental data in the literature with the method and parameter values we determined. We examined the effects of phonon excitations in projectile and target nuclei on fusion cross sections and barrier distributions. With our research, we showed that the coupled channel model and the calculation codes used to explain the fusion cross-section data and barrier distributions well. This research sheds light on the importance of analyzing important medical radionuclides such as At 211 by heavy-ion fusion reactions and encourages new researches.